PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2555220-0	1989	A type 2A protein phosphatase dephosphorylates the elongation factor 2 and is stimulated by the phorbol ester TPA in mouse epidermis in vivo.	Tetradecanoylphorbol Acetate	110-113	eukaryotic translation elongation factor 2	Mus musculus	51-70	
2555220-1	1989	Mouse epidermal cytosol contains a protein phosphatase with Mr 38,000, which dephosphorylates the elongation factor 2 (EF-2) of protein biosynthesis and is stimulated after topical application of TPA to mouse skin [(1988) Biochem.	Tetradecanoylphorbol Acetate	196-199	eukaryotic translation elongation factor 2	Mus musculus	98-117	
2555220-1	1989	Mouse epidermal cytosol contains a protein phosphatase with Mr 38,000, which dephosphorylates the elongation factor 2 (EF-2) of protein biosynthesis and is stimulated after topical application of TPA to mouse skin [(1988) Biochem.	Tetradecanoylphorbol Acetate	196-199	eukaryotic translation elongation factor 2	Mus musculus	119-123	
2555220-10	1989	These data indicate that the TPA-stimulated EF-2 phosphatase in epidermal cytosol is a type 2A protein phosphatase.	Tetradecanoylphorbol Acetate	29-32	eukaryotic translation elongation factor 2	Mus musculus	44-48	
2471685-0	1989	The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo.	Tetradecanoylphorbol Acetate	190-193	eukaryotic translation elongation factor 2	Mus musculus	117-136	
2471685-1	1989	Similar to previous observations with cyclosporins and didemnin B, the novel immunosuppressant FK-506 inhibits the Ca2+/calmodulin-dependent phosphorylation of the eukaryotic elongation factor 2 of protein synthesis in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo.	Tetradecanoylphorbol Acetate	269-272	eukaryotic translation elongation factor 2	Mus musculus	175-194	
3390175-0	1988	Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: stimulation of an elongation factor 2 phosphatase activity by TPA in vivo.	Tetradecanoylphorbol Acetate	40-43	eukaryotic translation elongation factor 2	Mus musculus	94-113	
3390175-0	1988	Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: stimulation of an elongation factor 2 phosphatase activity by TPA in vivo.	Tetradecanoylphorbol Acetate	138-141	eukaryotic translation elongation factor 2	Mus musculus	94-113	
3390175-1	1988	Topical application of the phorbol ester TPA to mouse skin causes an increase in the amount of elongation factor 2 (EF-2), a factor in eukaryotic protein synthesis, in the epidermal cytosol (2- to 3-fold) and particulate fraction (7-fold).	Tetradecanoylphorbol Acetate	41-44	eukaryotic translation elongation factor 2	Mus musculus	95-114	
3390175-1	1988	Topical application of the phorbol ester TPA to mouse skin causes an increase in the amount of elongation factor 2 (EF-2), a factor in eukaryotic protein synthesis, in the epidermal cytosol (2- to 3-fold) and particulate fraction (7-fold).	Tetradecanoylphorbol Acetate	41-44	eukaryotic translation elongation factor 2	Mus musculus	116-120	
3390175-2	1988	Furthermore, as a consequence of this TPA treatment the activity of an epidermal EF-2 phosphatase is stimulated.	Tetradecanoylphorbol Acetate	38-41	eukaryotic translation elongation factor 2	Mus musculus	81-85	
3390175-5	1988	Both of the TPA-induced effects result in an increase in unphosphorylated, i.e. active EF-2 and can be suppressed by cyclosporine A.	Tetradecanoylphorbol Acetate	12-15	eukaryotic translation elongation factor 2	Mus musculus	87-91	
3342035-3	1988	Furthermore, CsH, like CsA, inhibits the Ca2+/calmodulin-dependent phosphorylation of the elongation factor 2 (EF-2) in vitro and the TPA-induced increases in the amount of EF-2 in vivo.	Tetradecanoylphorbol Acetate	134-137	eukaryotic translation elongation factor 2	Mus musculus	111-115	
3342035-3	1988	Furthermore, CsH, like CsA, inhibits the Ca2+/calmodulin-dependent phosphorylation of the elongation factor 2 (EF-2) in vitro and the TPA-induced increases in the amount of EF-2 in vivo.	Tetradecanoylphorbol Acetate	134-137	eukaryotic translation elongation factor 2	Mus musculus	173-177	
3342035-6	1988	Inhibition of TPA-effects may involve suppression of calmodulin-dependent processes, such as augmentation and phosphorylation of EF-2.	Tetradecanoylphorbol Acetate	14-17	eukaryotic translation elongation factor 2	Mus musculus	129-133	
3273203-5	1988	Since CsA inhibits specifically 12-O-tetradecanoylphorbol-13-acetate (TAP)-stimulated but not basal protein synthesis in epidermis, it is proposed that Ca2+/calmodulin-dependent phosphorylation of EF-2 is involved in the induction of the hyperplastic response by TPA and that CsA suppresses TPA effects by inhibition of EF-2-phosphorylation and perhaps other calmodulin-dependent processes.	Tetradecanoylphorbol Acetate	32-68	eukaryotic translation elongation factor 2	Mus musculus	197-201