PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7784702-0 1995 Differing kinase activity of the c-yes and c-src gene proteins in TPA-induced megakaryocytic differentiation of T-33 and K562 cell lines. Tetradecanoylphorbol Acetate 66-69 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 33-38 7784702-1 1995 We examined the protein kinase (PK) activity of the c-yes and c-src gene proteins (c-YES, c-SRC) at an early phase of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced megakaryocytic differentiation of T-33 and K562 cells with use of immunoprecipitation and in vitro kinase assay. Tetradecanoylphorbol Acetate 118-155 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 52-57 7784702-1 1995 We examined the protein kinase (PK) activity of the c-yes and c-src gene proteins (c-YES, c-SRC) at an early phase of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced megakaryocytic differentiation of T-33 and K562 cells with use of immunoprecipitation and in vitro kinase assay. Tetradecanoylphorbol Acetate 118-155 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 83-88 7784702-1 1995 We examined the protein kinase (PK) activity of the c-yes and c-src gene proteins (c-YES, c-SRC) at an early phase of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced megakaryocytic differentiation of T-33 and K562 cells with use of immunoprecipitation and in vitro kinase assay. Tetradecanoylphorbol Acetate 157-160 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 52-57 7784702-1 1995 We examined the protein kinase (PK) activity of the c-yes and c-src gene proteins (c-YES, c-SRC) at an early phase of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced megakaryocytic differentiation of T-33 and K562 cells with use of immunoprecipitation and in vitro kinase assay. Tetradecanoylphorbol Acetate 157-160 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 83-88 7784702-3 1995 We also examined PK activity in TPA-induced monocytic differentiation of U937 monoblastic cells that exhibited no megakaryocytic markers and found that both the c-YES and c-SRC PK activity was enhanced by the TPA treatment. Tetradecanoylphorbol Acetate 32-35 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 161-166 7784702-3 1995 We also examined PK activity in TPA-induced monocytic differentiation of U937 monoblastic cells that exhibited no megakaryocytic markers and found that both the c-YES and c-SRC PK activity was enhanced by the TPA treatment. Tetradecanoylphorbol Acetate 209-212 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 161-166 7784702-4 1995 Our data suggest that c-YES and c-SRC play different and unique roles in TPA-induced megakaryocytic differentiation in T-33 and K562 cells. Tetradecanoylphorbol Acetate 73-76 YES proto-oncogene 1, Src family tyrosine kinase Homo sapiens 22-27