PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
581059-4	1978	Induction of AHH by MC was markedly inhibited by SO2, only slightly by mixture of NO2-SO2 but not with NO2 alone.	Sulfur Dioxide	49-52	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	13-16	
16023800-0	2005	Effect of sulfur dioxide inhalation on CYP1A1 and CYP1A2 in rat liver and lung.	Sulfur Dioxide	10-24	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	39-45	
16023800-6	2005	In the liver, a decrease down to 0.68- and 0.64-fold in the CYP1A1 activity, probed by the O-deethylation of ethoxyresorufin (EROD), was observed at higher dose of SO2 (28 and 56 mg/m3); Similarly, CYP1A1 mRNA levels were reduced in livers of rats exposed to SO2 at 28 and 56 mg/m3.	Sulfur Dioxide	164-167	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	60-66	
16023800-6	2005	In the liver, a decrease down to 0.68- and 0.64-fold in the CYP1A1 activity, probed by the O-deethylation of ethoxyresorufin (EROD), was observed at higher dose of SO2 (28 and 56 mg/m3); Similarly, CYP1A1 mRNA levels were reduced in livers of rats exposed to SO2 at 28 and 56 mg/m3.	Sulfur Dioxide	164-167	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	198-204	
16023800-6	2005	In the liver, a decrease down to 0.68- and 0.64-fold in the CYP1A1 activity, probed by the O-deethylation of ethoxyresorufin (EROD), was observed at higher dose of SO2 (28 and 56 mg/m3); Similarly, CYP1A1 mRNA levels were reduced in livers of rats exposed to SO2 at 28 and 56 mg/m3.	Sulfur Dioxide	259-262	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	60-66	
16023800-10	2005	SO2 at higher concentrations (28 and 56 mg/m3) decreased significantly pulmonary CYP1A1 and 1A2 mRNA levels relative to control animals.	Sulfur Dioxide	0-3	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	81-95	
16023800-12	2005	These results lead to the conclusion that SO2 exposure can reduce CYP1A1 and 1A2 in lungs and livers of rats and ROS and/or cytokines might act as mediators of this effect according to previous studies performed in mice.	Sulfur Dioxide	42-45	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	66-80	
16616405-6	2006	In lungs of rats exposed to SO2 alone, the gene transcription of CYP1A1 and 1A2, the EROD and MROD activities were decreased.	Sulfur Dioxide	28-31	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	65-71