PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34998792-0 2022 Endoplasmic reticulum stress-dependent activation of TRB3-FoxO1 signaling pathway exacerbates hyperglycemic nephrotoxicity: Protection accorded by naringenin. naringenin 147-157 tribbles pseudokinase 3 Rattus norvegicus 53-57 34998792-5 2022 Treatment with Naringenin reduced the expression of TRB3, an ER stress-inducible pseudokinase, both in vitro and in vivo. naringenin 15-25 tribbles pseudokinase 3 Rattus norvegicus 52-56 34998792-11 2022 These findings affirm that activation of TRB3-FoxO1 signaling is critical in the pathogenesis of hyperglycemia-induced renal toxicity and protective effect of Naringenin via modulation of ER stress may be exploited as a novel approach for its management. naringenin 159-169 tribbles pseudokinase 3 Rattus norvegicus 41-45