PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30208590-6 2018 RESULTS: Adenine mice exhibited significantly higher mean serum urea, creatinine, and renal expression of the pro-inflammatory markers Interleukin-6 (IL-6), C-X-C motif chemokine 10 (CXCL10), and Interleukin-1beta (IL-1beta), in addition to prominent renal fibrosis and reduced renal Klotho gene expression compared to the control. Adenine 9-16 interleukin 6 Mus musculus 135-148 30208590-6 2018 RESULTS: Adenine mice exhibited significantly higher mean serum urea, creatinine, and renal expression of the pro-inflammatory markers Interleukin-6 (IL-6), C-X-C motif chemokine 10 (CXCL10), and Interleukin-1beta (IL-1beta), in addition to prominent renal fibrosis and reduced renal Klotho gene expression compared to the control. Adenine 9-16 interleukin 6 Mus musculus 150-154 29962852-7 2018 In RAW264.7 cells stimulated with LPS, adenine inhibited production of pro-inflammatory cytokines TNF-alpha and IL-6 and inflammatory lipid mediators, prostaglandin E2 and leukotriene B4. Adenine 39-46 interleukin 6 Mus musculus 112-116 29962852-11 2018 In BMMCs, adenine inhibited the LPS-induced production of TNF-alpha, IL-6 and IL-13 and also hindered phosphorylation of NF-kappaB and Akt. Adenine 10-17 interleukin 6 Mus musculus 69-73 29962852-12 2018 In peritoneal cavity, adenine suppressed the LPS-induced production of TNF-alpha and IL-6 by peritoneal cells in mice. Adenine 22-29 interleukin 6 Mus musculus 85-89 29861060-4 2018 IL-6 knock-out mice fed an adenine diet to induce CKD failed to increase bone FGF23 mRNA and had a muted increase in serum FGF23 levels, compared with the increases in wild-type mice with CKD. Adenine 27-34 interleukin 6 Mus musculus 0-4 27440777-7 2016 WT adenine-fed mice were anemic and had low serum iron, elevated Hamp, and elevated IL6 and TNF-alpha. Adenine 3-10 interleukin 6 Mus musculus 84-87