PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11781084-4 2002 In this model, nucleotide binding to the specificity site (s-site) drives formation of an active R1(2)R2(2) dimer, ATP or dATP binding to the adenine-specific site (a-site) results in formation of an inactive tetramer, and ATP binding to the newly described hexamerization site (h-site) drives formation of active R1(6)R2(6) hexamer. Adenine 142-149 ribonucleotide reductase M2 Mus musculus 102-104 11781084-4 2002 In this model, nucleotide binding to the specificity site (s-site) drives formation of an active R1(2)R2(2) dimer, ATP or dATP binding to the adenine-specific site (a-site) results in formation of an inactive tetramer, and ATP binding to the newly described hexamerization site (h-site) drives formation of active R1(6)R2(6) hexamer. Adenine 142-149 ribonucleotide reductase M2 Mus musculus 319-321