PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31437443-4 2020 To overcome these limitations, we applied an A T G C adenine base editor (ABE) to correct two different COL7A1 mutations in primary fibroblasts derived from RDEB patients. Adenine 53-60 collagen type VII alpha 1 chain Homo sapiens 104-110 32142798-7 2020 Next generation sequencing of the on-target site revealed the presence of the precise adenine insertion upstream of the pathogenic mutation in at least 17% of all analyzed COL7A1 alleles. Adenine 86-93 collagen type VII alpha 1 chain Homo sapiens 172-178