PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15885468-2	2005	We hypothesized that the absence of the IL-1 type-1 receptor would mitigate the inflammatory response to titanium particles and decrease periprosthetic inflammatory tissue in a murine intramedullary rod model.	Titanium	105-113	interleukin 1 complex	Mus musculus	40-44	
17618512-3	2008	Titanium is a commonly utilized metal in joint arthroplasty and titanium debris induces the production of the pro-inflammatory cytokine IL-1.	Titanium	0-8	interleukin 1 complex	Mus musculus	136-140	
17618512-3	2008	Titanium is a commonly utilized metal in joint arthroplasty and titanium debris induces the production of the pro-inflammatory cytokine IL-1.	Titanium	64-72	interleukin 1 complex	Mus musculus	136-140	
15885468-9	2005	CONCLUSIONS: These results implicate IL-1 as an important modulator in the local inflammatory response to intramedullary titanium particles.	Titanium	121-129	interleukin 1 complex	Mus musculus	37-41	
12115237-4	2002	RESULTS: In the presence of AdLacZ-infected FLS, titanium particle-stimulated macrophages exhibited a marked increase in secretion of tumor necrosis factor alpha (TNFalpha) (6.5-fold), IL-6 (13-fold), and IL-1 (5-fold).	Titanium	49-57	interleukin 1 complex	Mus musculus	205-209