PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8244393-1 1993 The Na+/glucose cotransporter gene SGLT1 encodes the primary carrier protein responsible for the uptake of the dietary sugars glucose and galactose from the intestinal lumen. Galactose 138-147 solute carrier family 5 member 1 Homo sapiens 35-40 32767111-7 2020 While SGLT1 is essential for fast absorption of glucose and galactose in the intestine, the expression of SGLT2 is largely confined to the early part of the kidney proximal tubules, where it reabsorbs the bulk part of filtered glucose. Galactose 60-69 solute carrier family 5 member 1 Homo sapiens 6-11 32829466-2 2020 SGLT1 and GLUT2 are relevant for absorption of D-glucose and D-galactose while GLUT5 is relevant for D-fructose absorption. Galactose 61-72 solute carrier family 5 member 1 Homo sapiens 0-5 31062524-7 2019 Dominant SGLT1 (SLC5A1) and SGLT3 (SLC5A4) expression was associated with the sigmoidal Ha/sLc glucose and La/Lc galactose transport systems in the jejunum. Galactose 113-122 solute carrier family 5 member 1 Homo sapiens 9-14 31062524-7 2019 Dominant SGLT1 (SLC5A1) and SGLT3 (SLC5A4) expression was associated with the sigmoidal Ha/sLc glucose and La/Lc galactose transport systems in the jejunum. Galactose 113-122 solute carrier family 5 member 1 Homo sapiens 16-22 28128227-5 2017 In cardiomyocytes, galactose (transported through SGLT1) did not activate NOX2. Galactose 19-28 solute carrier family 5 member 1 Homo sapiens 50-55 23886446-10 2013 In summary, the direct addition of IL-1beta to intestinal epithelia inhibits d-galactose transport by a possible reduction in the SGLT1 activity. Galactose 77-88 solute carrier family 5 member 1 Homo sapiens 130-135 26548423-1 2015 INTRODUCTION: SGLT1 is the primary transporter responsible for the absorption of glucose and galactose in the intestine, while SGLT2 and SGLT1 are both involved in the renal reabsorption of glucose. Galactose 93-102 solute carrier family 5 member 1 Homo sapiens 14-19 17956309-1 2007 SGLT1 (Na(+)/glucose co-transporter 1) transports the dietary sugars, D-glucose and D-galactose, from the lumen of the intestine into enterocytes. Galactose 84-95 solute carrier family 5 member 1 Homo sapiens 0-5 17956309-1 2007 SGLT1 (Na(+)/glucose co-transporter 1) transports the dietary sugars, D-glucose and D-galactose, from the lumen of the intestine into enterocytes. Galactose 84-95 solute carrier family 5 member 1 Homo sapiens 7-37 17495124-5 2007 The inhibitory potency remained unchanged when the attached glucose was replaced by galactose, suggesting that these residues may bind to SGLT1. Galactose 84-93 solute carrier family 5 member 1 Homo sapiens 138-143 17288452-5 2007 In the absence of sodium, various sugars significantly decreased the intrinsic Trp fluorescence of hSGLT1 in proteoliposomes exhibiting the following sequence of affinities: alpha-MDG > d-glucose approximately d-galactose > 6-deoxy-d-glucose > 2-deoxy-d-glucose > d-allose. Galactose 213-224 solute carrier family 5 member 1 Homo sapiens 99-105 17110502-5 2007 However, specificity of hSGLT3 binding is greater (D-galactose and 4-deoxy-4-fluoro-D-galactose are not hSGLT3 substrates, but have hSGLT1 K0.5 values of 0.6 and 1.3 mM). Galactose 51-62 solute carrier family 5 member 1 Homo sapiens 132-138 14642859-5 2003 Mutations in SGLT1 cause a major defect in glucose and galactose absorption (glucose-galactose Malabsorption), but mutations in GLUT2 do not appear to disrupt glucose and galactose absorption. Galactose 55-64 solute carrier family 5 member 1 Homo sapiens 13-18 16204409-1 2006 SGLT1 (SLC5A1) mediates a part of glucose and galactose reabsorption in the mammalian proximal tubule (PT), but the detailed localization of the transporter along the tubule is still disputable. Galactose 46-55 solute carrier family 5 member 1 Homo sapiens 0-5 16204409-1 2006 SGLT1 (SLC5A1) mediates a part of glucose and galactose reabsorption in the mammalian proximal tubule (PT), but the detailed localization of the transporter along the tubule is still disputable. Galactose 46-55 solute carrier family 5 member 1 Homo sapiens 7-13 14521930-7 2003 We suggest that glucose or galactose, through an interaction with SGLT1, activates a protein kinase C pathway that regulates the activity of one of the intestinal cholesterol transporters, namely hSR-BI. Galactose 27-36 solute carrier family 5 member 1 Homo sapiens 66-71 10762614-1 2000 The Na(+)-glucose cotransporter (SGLT1) is expressed primarily by small intestinal epithelial cells and transports the monosaccharides glucose and galactose across the apical membrane. Galactose 147-156 solute carrier family 5 member 1 Homo sapiens 33-38 11602601-1 2001 The Na(+)/glucose cotransporter (SGLT1) is highly selective for its natural substrates, d-glucose and d-galactose. Galactose 102-113 solute carrier family 5 member 1 Homo sapiens 33-38 10997927-9 2000 Glucose uptake was inhibited by the treatment with SGLT-1 antisense and D-galactose. Galactose 72-83 solute carrier family 5 member 1 Homo sapiens 51-57 9729444-1 1998 The intestinal transport of glucose- and galactose-conjugated acetaminophen (APAP glycoside) by Na+/glucose cotransporter (SGLT1) was studied. Galactose 41-50 solute carrier family 5 member 1 Homo sapiens 123-128 8195156-1 1994 Intestinal uptake of dietary glucose and galactose is mediated by the SGLT1 Na+/glucose cotransporter of the brush border. Galactose 41-50 solute carrier family 5 member 1 Homo sapiens 70-75