PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9835525-9 1998 The addition of CAP18106-137 to aztreonam along with the bacteria did decrease the level of antibiotic-induced release of inflammatory mediators including tumor necrosis factor alpha, interleukin-6, and nitric oxide and also improved the survival of the mice. Aztreonam 32-41 tumor necrosis factor Mus musculus 155-182 12935353-2 2003 Ceftazidime and aztreonam enhanced TNF-alpha secretion from macrophages stimulated with E. coli; however, imipenem does not alter either the kinetics or magnitude of TNF-alpha in E. coli-treated macrophages. Aztreonam 16-25 tumor necrosis factor Mus musculus 35-44 12935353-6 2003 Both ceftazidime and aztreonam enhanced LPS release from E. coli in comparison to low-level LPS release from imipenem-treated bacteria, consistent with observed differences in TNF-alpha release. Aztreonam 21-30 tumor necrosis factor Mus musculus 176-185 9529499-9 1998 Both continuous metronidazole and aztreonam reduced lung MPO concentration (P < 0.05) and TNF-alpha and IL-1 beta mRNA expression (P < 0.05) compared with those in saline controls. Aztreonam 34-43 tumor necrosis factor Mus musculus 93-102