PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2282121-1 1990 The substituted 3-aminoxyproprionyl (VII) and 3-aminoxy-(E)-2-methoxyiminopropionyl monobactams (VIII) which possess the monocyclic beta-lactam nucleus of aztreonam (IX) were synthesized by reaction of triethylammonium (3S, 4S)-3-amino-4-methyl-2-oxo-1-azetidinsulfonate with the aminoxy acids X and XI, respectively. Aztreonam 155-164 cytochrome c oxidase subunit 8A Homo sapiens 97-101 2282121-4 1990 On the contrary VII and VIII proved to be practically inactive against Gram-negative microorganisms, towards which aztreonam exhibits a high degree of activity. Aztreonam 115-124 cytochrome c oxidase subunit 8A Homo sapiens 24-28