PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1702789-8	1990	These experiments demonstrate that agonist-induced tyrosine phosphorylation is linked to the process of GP IIb-IIIa-mediated platelet aggregation.	Tyrosine	51-59	integrin subunit alpha 2b	Homo sapiens	104-110	
7520434-2	1994	A single amino acid substitution in beta 3 (Asp119 --> Tyr) abrogates the ligand binding function of beta 3 integrins and alters the divalent cation conformation of the platelet integrin alpha IIb beta 3 (GPIIb-IIIa).	Tyrosine	58-61	integrin subunit alpha 2b	Homo sapiens	208-213	
1400325-10	1992	Association of pp60src and GpIIb/IIIa with the cytoskeleton and slow tyrosine phosphorylation are related phenomena.	Tyrosine	69-77	integrin subunit alpha 2b	Homo sapiens	27-32	
1856198-7	1991	Amino-terminal sequencing of a tryptic fragment labeled with [35S]ATP-alpha-S identified an 18-kDa domain beginning at Tyr-198 in the primary sequence of GPIIb alpha.	Tyrosine	119-122	integrin subunit alpha 2b	Homo sapiens	154-159	
1716898-2	1991	2E7 is a human monoclonal IgM autoantibody, derived from splenocytes of a patient with ITP, that recognizes a specific octapeptide amino acid sequence, Phe-Asp-Gly-Tyr-Trp-Gly-Tyr-Ser, on the heavy chain of GPIIb.	Tyrosine	164-167	integrin subunit alpha 2b	Homo sapiens	207-212	
12588350-11	2003	Clopidogrel and SR121566 inhibited the increase in tyrosine phosphorylation induced by 2MesADP and concomitantly inhibited platelet aggregation, indicating that most of the phosphorylations are GPIIb/IIIa dependent.	Tyrosine	51-59	integrin subunit alpha 2b	Homo sapiens	194-199	
12590956-6	2002	A positive correlation is observed between inhibition of clot retraction and inhibition of tyrosine dephosphorylation across a number of GP IIb/IIIa antagonist pharmacophores.	Tyrosine	91-99	integrin subunit alpha 2b	Homo sapiens	137-143	
11929319-1	2002	Tirofiban is a nonpeptide tyrosine derivative that antagonises platelet glycoprotein IIb/IIIa (GP IIb/IIIa) receptors.	Tyrosine	26-34	integrin subunit alpha 2b	Homo sapiens	95-101	
11728525-6	2001	Focal adhesion kinase tyrosine phosphorylation induced by TRAP is blocked by these GPIIb/IIIa antagonists, but restored by pl-62 crosslinking independent of LIBS induction.	Tyrosine	22-30	integrin subunit alpha 2b	Homo sapiens	83-88	
11333182-3	2001	Moreover, in von Willebrand factor-stimulated platelets, the tyrosine phosphorylation of pp60(c-src) is closely associated with the activation of phosphatidylinositol 3-kinase (PIK), and two adhesion receptors, glycoprotein (Gp)Ib and GpIIb/IIIa(alpha-IIb-beta(3)), are involved.	Tyrosine	61-69	integrin subunit alpha 2b	Homo sapiens	235-240	
9063461-5	1997	By analysing functional platelet responses and protein-tyrosine phosphorylation, we found that such non-Fc gamma RII-mediated cross-linking of CD9, CD42 and glycoprotein (gp) IIb/IIIa generates closely similar signals.	Tyrosine	55-63	integrin subunit alpha 2b	Homo sapiens	157-178	
7482416-8	1995	KRDS strongly inhibits the tyrosine-phosphorylated substrates, in particular two 100-105 kDa substrates which are related to GP IIb/IIIa activation and platelet aggregation.	Tyrosine	27-35	integrin subunit alpha 2b	Homo sapiens	125-131	
2452517-6	1988	Reactivity of a second monoclonal, 9-7.9 (epitope GP-2B) but not 33.6, was abolished when substitution of tyrosine for phenylalanine was made at position 375 in the antigenic sequence corresponding to a naturally occurring sequence difference between LCM and Lassa viruses.	Tyrosine	106-114	integrin subunit alpha 2b	Homo sapiens	50-55	
16837624-6	2006	By investigating how MNS inhibits GPIIb/IIIa activation, we found that MNS potently inhibited the activity of tyrosine kinases (Src and Syk) and prevented protein tyrosine phosphorylation and cytoskeletal association of GPIIb/IIIa and talin, but it had no direct effects on protein kinase C, Ca2+ mobilization, Ca2+-dependent enzymes (myosin light chain kinase and calpain), and arachidonic acid metabolism, and it did not affect the cellular levels of cyclic nucleotides.	Tyrosine	110-118	integrin subunit alpha 2b	Homo sapiens	34-39