PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28655771-3 2017 We found that, among the RhoGEFs tested, MCP1 induced tyrosine phosphorylation of p115 RhoGEF but not of PDZ RhoGEF or leukemia-associated RhoGEF in human aortic smooth muscle cells (HASMCs). Tyrosine 54-62 Rho guanine nucleotide exchange factor 1 Homo sapiens 82-93 25870189-4 2015 In vitro stimulation of human coronary artery smooth muscle cells and human peripheral blood mononuclear cells by Ang II (0.1 mumol/L) induced activation of Arhgef1 attested by its increased tyrosine phosphorylation. Tyrosine 191-199 Rho guanine nucleotide exchange factor 1 Homo sapiens 157-164 24025335-3 2013 Thrombin induced tyrosine phosphorylation of Pyk2, Gab1, and p115 RhoGEF, leading to Rac1- and RhoA-dependent Pak2 activation. Tyrosine 17-25 Rho guanine nucleotide exchange factor 1 Homo sapiens 61-72 27986909-7 2017 Accordingly, SOS1, ARHGEF1, and DOCK2 are tyrosine phosphorylated upon chemokine signaling with timing coherent with rapid LFA-1 affinity activation. Tyrosine 42-50 Rho guanine nucleotide exchange factor 1 Homo sapiens 19-26 27986909-9 2017 Unexpectedly, and differently from VAV1, tyrosine phosphorylation of SOS1, ARHGEF1, and DOCK2 is completely inhibited by pertussis toxin pretreatment, thus suggesting different routes of rho-GEF triggering upon CXCR4 engagement. Tyrosine 41-49 Rho guanine nucleotide exchange factor 1 Homo sapiens 75-82