PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20543098-6 2010 During IL-15-mediated NK cell priming, SOCS2 interacted with phosphorylated proline-rich tyrosine kinase 2 (Pyk2) at tyrosine 402 (p-Pyk2(Tyr402)) and induced the proteasome-mediated degradation of p-Pyk2(Tyr402) via ubiquitination. Tyrosine 89-97 interleukin 15 Homo sapiens 7-12 26425665-0 2015 SILAC-based quantification of changes in protein tyrosine phosphorylation induced by Interleukin-2 (IL-2) and IL-15 in T-lymphocytes. Tyrosine 49-57 interleukin 15 Homo sapiens 110-115 12459483-4 2002 IL-15 was found to induce tyrosine phosphorylation events and to prevent loss of the anti-apoptotic Mcl-1 protein expression. Tyrosine 26-34 interleukin 15 Homo sapiens 0-5 15123770-9 2004 In addition, IL-15 was found to induce tyrosine phosphorylation of Syk that was largely inhibited by pretreating cells with piceatannol. Tyrosine 39-47 interleukin 15 Homo sapiens 13-18 9811525-4 1998 As determined by tyrosine phosphorylation, nuclear translocation and binding to an hSIE-oligonucleotide probe, IL-2 and IL-15 activated the slowly migrating isoform, Stat3alpha. Tyrosine 17-25 interleukin 15 Homo sapiens 120-125 11340297-0 2001 Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a. Tyrosine 26-34 interleukin 15 Homo sapiens 54-68 11340297-4 2001 IL-15, but not IL-4, also induced tyrosine phosphorylation of Gab2, suggesting that the IL-2 receptor beta-chain is important for IL-2-induced Gab2 phosphorylation. Tyrosine 34-42 interleukin 15 Homo sapiens 0-5 8978277-4 1997 EPO, IL-2, and IL-15 activated the tyrosine phosphorylation of the adaptor protein, Shp2, and the association of Shp2/Grb2/cytokine receptor complexes. Tyrosine 35-43 interleukin 15 Homo sapiens 15-20 9126349-5 1997 We report that IL-15 induces tyr phosphorylation of the p75IL-2R beta and p64IL-2R gamma subunits and Shc. Tyrosine 29-32 interleukin 15 Homo sapiens 15-20 8978277-3 1997 Although stimulation with IL-2 or IL-15 resulted in the rapid, dose-dependent tyrosine phosphorylation of Shc, stimulation with EPO failed to activate Shc. Tyrosine 78-86 interleukin 15 Homo sapiens 34-39 7568001-4 1995 IL-2 and IL-15 rapidly induced the tyrosine phosphorylation of STAT3 and STAT5, and DNA-binding complexes containing STAT3 and STAT5 were rapidly activated by these cytokines in T cells. Tyrosine 35-43 interleukin 15 Homo sapiens 9-14 8647198-4 1996 This leads to a decreased responsiveness to IL-15 as measured by induction of Jak3 tyrosine phosphorylation. Tyrosine 83-91 interleukin 15 Homo sapiens 44-49 7568001-6 1995 JAK1 and JAK3 were tyrosine-phosphorylated in response to IL-2 and IL-15. Tyrosine 19-27 interleukin 15 Homo sapiens 67-72 7719938-3 1995 IL-7 and IL-15 induced the same complexes as IL-2, a feature explained by the existence of similar tyrosine-phosphorylated motifs in the cytoplasmic domains of IL-2R beta and IL-7R that can serve as docking sites for Stat proteins. Tyrosine 99-107 interleukin 15 Homo sapiens 9-14 29939941-4 2019 He presents with preserved STAT5 tyrosine phosphorylation in response to IL-15 stimulation but not in response to IL-2 and IL-7, resulting in the NK phenotype. Tyrosine 33-41 interleukin 15 Homo sapiens 73-78