PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9581570-0 1997 A tyrosine residue essential for catalytic activity in aminopeptidase A. Tyrosine 2-10 glutamyl aminopeptidase Mus musculus 55-71 25637494-1 2015 An earlier study has demonstrated that exogenous allopregnanolone (APalpha) can reverse the reduction of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra pars compacta (SNpc) of 3-month-old male triple transgenic Alzheimer"s disease mouse (3xTgAD). Tyrosine 105-113 glutamyl aminopeptidase Mus musculus 67-74 9581570-3 1997 Treatment of APA with N-acetylimidazole results in a loss of enzymic activity; this is prevented by the competitive aminopeptidase inhibitor amastatin, suggesting the presence of an important tyrosine, lysine or cysteine residue at the active site of APA. Tyrosine 192-200 glutamyl aminopeptidase Mus musculus 13-16 9581570-5 1997 Furthermore sequence alignment of mouse APA with other monozinc aminopeptidases indicates the presence of a conserved tyrosine (Tyr-471 in APA). Tyrosine 118-126 glutamyl aminopeptidase Mus musculus 40-43 9581570-5 1997 Furthermore sequence alignment of mouse APA with other monozinc aminopeptidases indicates the presence of a conserved tyrosine (Tyr-471 in APA). Tyrosine 118-126 glutamyl aminopeptidase Mus musculus 139-142 9581570-5 1997 Furthermore sequence alignment of mouse APA with other monozinc aminopeptidases indicates the presence of a conserved tyrosine (Tyr-471 in APA). Tyrosine 128-131 glutamyl aminopeptidase Mus musculus 40-43 9581570-5 1997 Furthermore sequence alignment of mouse APA with other monozinc aminopeptidases indicates the presence of a conserved tyrosine (Tyr-471 in APA). Tyrosine 128-131 glutamyl aminopeptidase Mus musculus 139-142 9581570-6 1997 The functional role of Tyr-471 in APA was investigated by replacing this residue with a phenylalanine (Phe-471) or a histidine (His-471) residue by site-directed mutagenesis. Tyrosine 23-26 glutamyl aminopeptidase Mus musculus 34-37