PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8405081-0	1993	Evaluation of truncated neuropeptide Y analogues with modifications of the tyrosine residue in position 1 on Y1, Y2 and Y3 receptor sub-types.	Tyrosine	75-83	neuropeptide Y	Rattus norvegicus	24-38	
7909929-3	1994	In an attempt to understand the effect of NPY on TH activities, an in vitro assay is carried out using chromatographic analysis of 3,4-dihydroxyphenylalanine (DOPA) formation from tyrosine.	Tyrosine	180-188	neuropeptide Y	Rattus norvegicus	42-45	
8405081-1	1993	Substitutions of the tyrosine residue in position 1 of truncated neuropeptide Y (N-terminal fragment 1-4 linked to C-terminal fragment 18-36 by the epsilon-aminocaproic acid) produced analogues that compete for specific [125I]polypeptide YY (PYY) binding in the frontoparietal cortex (Y1-enriched) with a profile best fitted to a two site-model with KD values in the low and high nM range, respectively.	Tyrosine	21-29	neuropeptide Y	Rattus norvegicus	65-79	
2172766-10	1990	This suggests that modifications of tyrosine residues at positions 20 and/or 21 may eventually lead to the development of NPY analogues distinguishing between the most abundant class of sites present in the brain and vas deferens, respectively.	Tyrosine	36-44	neuropeptide Y	Rattus norvegicus	122-125	
2342055-7	1990	A critical loss of potency of hNPY was also observed after the substitution of the Tyr-1 residue by L-Ala, thus confirming the important role played by this residue for the full expression of the biological activity of NPY.	Tyrosine	83-86	neuropeptide Y	Rattus norvegicus	31-34	
2156850-4	1990	In addition, certain species of radiolabeled NPY, including those labeled with IODO-GEN at the tyrosine residue 36, also demonstrated an ability to bind to brush-border membranes.	Tyrosine	95-103	neuropeptide Y	Rattus norvegicus	45-48	
2571139-0	1989	Neuropeptide tyrosine (NPY)-induced potentiation of the pressor activity of catecholamines in conscious rats.	Tyrosine	13-21	neuropeptide Y	Rattus norvegicus	23-26	
2237785-4	1990	In these studies, we have focused on defining the efferent targets of LC neurons that contain neuropeptide tyrosine (NPY)-like immunoreactivity.	Tyrosine	107-115	neuropeptide Y	Rattus norvegicus	117-120	
2843832-4	1988	Complete amino acid sequence of NPY is required for full agonist activity; deletion of tyrosine at the amino terminus, i.e., NPY fragment 2-36 was 3-fold less potent than the native peptide.	Tyrosine	87-95	neuropeptide Y	Rattus norvegicus	125-128	
10762361-1	2000	The hippocampus is particularly enriched with neuropeptide tyrosine (NPY) and NPY receptors including the Y1, Y2 and Y5 subtypes.	Tyrosine	59-67	neuropeptide Y	Rattus norvegicus	69-72	
3277713-0	1988	Fine-structural localization of neuropeptide tyrosine (NPY)-like immunoreactivity in the neuronal somata of colchicine-pretreated celiac ganglia of rats.	Tyrosine	45-53	neuropeptide Y	Rattus norvegicus	55-58	
2872078-0	1986	"Neuropeptide tyrosine" (NPY) is co-stored with noradrenaline in vascular but not in parenchymal sympathetic nerves of brown adipose tissue.	Tyrosine	14-22	neuropeptide Y	Rattus norvegicus	25-28	
2872078-2	1986	In contrast, "neuropeptide tyrosine" (NPY) is selectively present in the vascular sympathetic nerves of the tissue--but not in nerves around brown fat cells.	Tyrosine	27-35	neuropeptide Y	Rattus norvegicus	38-41	
3516014-0	1986	Neuropeptide tyrosine (NPY)-like immunoreactivity in adrenal chromaffin cells and intraadrenal nerve fibers of rats.	Tyrosine	13-21	neuropeptide Y	Rattus norvegicus	23-26	
23123350-1	2013	Previous work has demonstrated that neuropeptide tyrosine (NPY), Y(1) receptor and Y(2) receptor are critical in modulation of pain after nerve injury.	Tyrosine	49-57	neuropeptide Y	Rattus norvegicus	59-62	
2821236-2	1987	Neuropeptide tyrosine (neuropeptide Y, NPY), a recently isolated endogenous brain peptide, reduces the extracellular population spike evoked by stimulation of stratum radiatum in area CA1 of the in vitro rat hippocampal slice, without reducing the antidromically evoked population spike.	Tyrosine	13-21	neuropeptide Y	Rattus norvegicus	23-37	
2821236-2	1987	Neuropeptide tyrosine (neuropeptide Y, NPY), a recently isolated endogenous brain peptide, reduces the extracellular population spike evoked by stimulation of stratum radiatum in area CA1 of the in vitro rat hippocampal slice, without reducing the antidromically evoked population spike.	Tyrosine	13-21	neuropeptide Y	Rattus norvegicus	39-42	
28062253-3	2017	In the present study, we explored temporal changes in the expression of the neuropeptides galanin and tyrosine (NPY) and their receptors (GalR1 and GalR2; Y1R and Y2R, respectively) in the injured spinal cord and evaluated the impact of PG administration on both neuropeptide systems and neuropathic behavior.	Tyrosine	102-110	neuropeptide Y	Rattus norvegicus	112-115	
11973010-1	2002	Inflammation induces an up-regulation of neuropeptide tyrosine (NPY) and its receptors in the dorsal horn, suggesting an important role in nociceptive transmission.	Tyrosine	54-62	neuropeptide Y	Rattus norvegicus	64-67	
9677306-9	1998	Taken together, our results suggest that stimulation of the NPY promoter by BDNF requires the simultaneous activation of two distinct pathways; one involves Shc and MAP kinase, and the other appears to be PLCgamma-independent but requires an intact tyrosine-785 on TrkB and so may involve an effector of TrkB signalling that remains to be identified.	Tyrosine	249-257	neuropeptide Y	Rattus norvegicus	60-63	
10737677-4	2000	[D-Tyr(27,36)D-Thr32]NPY(27-36) was active only in subconvulsive dose.	Tyrosine	2-6	neuropeptide Y	Rattus norvegicus	21-24	
8841913-2	1996	The large neuropeptide tyrosine (NPY)-expressing ganglion neurons (type I ganglion neurons) matured postnatally, with marked increases in acetylcholinesterase (AChE)-, neurofilament 10 (NF10)-, and tyrosine hydroxylase (TH)-like immunoreactivities (LIs) paralleled by increasing levels of mRNAs encoding NPY, low-affinity neurotrophin receptor (LANR), and tropomyosin kinase receptor (trk).	Tyrosine	23-31	neuropeptide Y	Rattus norvegicus	33-36	
10904528-0	1998	Neuropeptide tyrosine-like immunoreactivity (NPY-LI) in ganglion neurons in the adrenal gland of the flat snake (Waglerophis merremii).	Tyrosine	13-21	neuropeptide Y	Rattus norvegicus	45-48	
7707318-1	1995	Peptide analogs of neuropeptide Y (NPY) with a Tyr-32 and Leu-34 replacement resulted in the decapeptide TyrIleAsnLeuIleTyrArgLeuArgTyr-NH2 (9; Table 1) and a 3700-fold improvement in affinity at Y2 (rat brain; IC50 = 8.2 +/- 3 nM) receptors when compared to the native NPY(27-36) C-terminal fragment.	Tyrosine	47-50	neuropeptide Y	Rattus norvegicus	19-33	
7707318-1	1995	Peptide analogs of neuropeptide Y (NPY) with a Tyr-32 and Leu-34 replacement resulted in the decapeptide TyrIleAsnLeuIleTyrArgLeuArgTyr-NH2 (9; Table 1) and a 3700-fold improvement in affinity at Y2 (rat brain; IC50 = 8.2 +/- 3 nM) receptors when compared to the native NPY(27-36) C-terminal fragment.	Tyrosine	47-50	neuropeptide Y	Rattus norvegicus	35-38