PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33922330-4 2021 In general, molecular imaging can depict the uptake and binding distribution of labelled hallucinogenic compounds or their congeners in the brain, as was shown in an early PET study with N1-([11C]-methyl)-2-bromo-LSD ([11C]-MBL); displacement with the non-radioactive competitor ketanserin confirmed that the majority of [11C]-MBL specific binding was to serotonin 5-HT2A receptors. Carbon-11 192-195 mannose-binding lectin family member 3, pseudogene Homo sapiens 224-227 2905532-1 1987 N1-([11C]-Methyl)-2-Br-LSD ([11C]-MBL) has been developed as a positron emission tomography (PET) imaging agent for serotonin 5-HT2 receptors. Carbon-11 5-8 mannose-binding lectin family member 3, pseudogene Homo sapiens 34-37 2905532-3 1987 Intravenous injection of [11C]-MBL in a baboon led to selective labeling of cortical regions that was markedly blocked by prior administration of ketanserin, a selective 5-HT2 receptor antagonist. Carbon-11 26-29 mannose-binding lectin family member 3, pseudogene Homo sapiens 31-34 2905532-4 1987 Clinical trials with [11C]-MBL have been conducted in seven normal human volunteers, and the regional distribution of radioactivity in the brain was distinctly serotonergic. Carbon-11 22-25 mannose-binding lectin family member 3, pseudogene Homo sapiens 27-30 2905532-9 1987 These studies indicate that [11C]-MBL is a selective radioligand that can be used to monitor serotonin 5-HT2 receptor densities in vivo in most regions of the human brain. Carbon-11 29-32 mannose-binding lectin family member 3, pseudogene Homo sapiens 34-37 33922330-4 2021 In general, molecular imaging can depict the uptake and binding distribution of labelled hallucinogenic compounds or their congeners in the brain, as was shown in an early PET study with N1-([11C]-methyl)-2-bromo-LSD ([11C]-MBL); displacement with the non-radioactive competitor ketanserin confirmed that the majority of [11C]-MBL specific binding was to serotonin 5-HT2A receptors. Carbon-11 192-195 mannose-binding lectin family member 3, pseudogene Homo sapiens 327-330