PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6317747-4 1984 All of these events may be related to activation of guanylate cyclase activity, since cyclic GMP also significantly reversed the suppressor effects of butylated hydroxyanisole in IFN gamma production. Butylated Hydroxyanisole 151-175 5'-nucleotidase, cytosolic II Mus musculus 93-96 6276334-1 1981 The effect of dibutyryl cyclic guanosine monophosphate (dbc-GMP) on butylated hydroxyanisole (BHA)-induced suppression of the primary in vitro thymus-dependent antibody response of BDF1 mouse spleen cultures was studied. Butylated Hydroxyanisole 68-92 5'-nucleotidase, cytosolic II Mus musculus 60-63 6276334-1 1981 The effect of dibutyryl cyclic guanosine monophosphate (dbc-GMP) on butylated hydroxyanisole (BHA)-induced suppression of the primary in vitro thymus-dependent antibody response of BDF1 mouse spleen cultures was studied. Butylated Hydroxyanisole 94-97 5'-nucleotidase, cytosolic II Mus musculus 60-63 6276334-2 1981 When added at 0 hr relative to antigen addition, 1 mg of dbc-GMP (8 mM) restored by greater than 70% the BHA-inhibited primary immunoglobulin (Ig)M plaque-forming cell (PFC) response to sheep erythrocytes (SRBC). Butylated Hydroxyanisole 105-108 5'-nucleotidase, cytosolic II Mus musculus 61-64 6276334-5 1981 Quantitation of c-GMP by radioimmunoassay demonstrated that BHA lowered by 58% the c-GMP content of splenic lymphocytes and abrogated the ability of lipopolysaccharide of E. coli (LPS) to elevate c-GMP levels in splenic lymphocytes. Butylated Hydroxyanisole 60-63 5'-nucleotidase, cytosolic II Mus musculus 18-21 6276334-5 1981 Quantitation of c-GMP by radioimmunoassay demonstrated that BHA lowered by 58% the c-GMP content of splenic lymphocytes and abrogated the ability of lipopolysaccharide of E. coli (LPS) to elevate c-GMP levels in splenic lymphocytes. Butylated Hydroxyanisole 60-63 5'-nucleotidase, cytosolic II Mus musculus 85-88 6276334-5 1981 Quantitation of c-GMP by radioimmunoassay demonstrated that BHA lowered by 58% the c-GMP content of splenic lymphocytes and abrogated the ability of lipopolysaccharide of E. coli (LPS) to elevate c-GMP levels in splenic lymphocytes. Butylated Hydroxyanisole 60-63 5'-nucleotidase, cytosolic II Mus musculus 85-88 6276334-6 1981 The data suggest that BHA exerts its immunosuppressive effect on the primary in vitro antibody response by inhibiting guanylate cyclase activity and effectively lowering c-GMP levels; exogenous dbc-GMP and Ca2+ can freely reverse the immunosuppressive effect of BHA. Butylated Hydroxyanisole 22-25 5'-nucleotidase, cytosolic II Mus musculus 172-175 6276334-6 1981 The data suggest that BHA exerts its immunosuppressive effect on the primary in vitro antibody response by inhibiting guanylate cyclase activity and effectively lowering c-GMP levels; exogenous dbc-GMP and Ca2+ can freely reverse the immunosuppressive effect of BHA. Butylated Hydroxyanisole 22-25 5'-nucleotidase, cytosolic II Mus musculus 198-201