PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28552457-0 2017 Butylated hydroxyanisole alters rat 5alpha-reductase and 3alpha-hydroxysteroid dehydrogenase: Implications for influences of neurosteroidogenesis. Butylated Hydroxyanisole 0-24 aldo-keto reductase family 1, member C14 Rattus norvegicus 57-92 28552457-5 2017 Butylated hydroxyanisole inhibited SRD5A1, AKR1C14, and RDH2 with IC50 values of 4.731+-0.079muM, 5.753+-0.073muM, and over 100muM, respectively. Butylated Hydroxyanisole 0-24 aldo-keto reductase family 1, member C14 Rattus norvegicus 43-50 28552457-6 2017 Butylated hydroxyanisole is a competitive inhibitor for both SRD5A1 and AKR1C14. Butylated Hydroxyanisole 0-24 aldo-keto reductase family 1, member C14 Rattus norvegicus 72-79 28552457-7 2017 Docking analysis shows that butylated hydroxyanisole binds to the dihydrotestosterone-binding site of AKR1C14. Butylated Hydroxyanisole 28-52 aldo-keto reductase family 1, member C14 Rattus norvegicus 102-109 28552457-8 2017 In conclusion, butylated hydroxyanisole is a potent inhibitor of SRD5A1 and AKR1C14, thus reducing the formation of active neurosteroids. Butylated Hydroxyanisole 15-39 aldo-keto reductase family 1, member C14 Rattus norvegicus 76-83