PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31497232-8 2019 Escin also attenuated the hepatic myeloperoxidase (MPO) activity and hepatic pro-inflammatory cytokines (i.e., TNF-alpha, IL-1beta, IL-6 and IL-17). Escin 0-5 interleukin 6 Mus musculus 132-136 26159678-4 2015 The effects of Escin on the release of pro-inflammatory cytokines such as TNF-alpha, IL-1beta, IL-6 and HMGB1 in the serum of endotoxemic mice and LPS-induced macrophages were evaluated by ELISA. Escin 15-20 interleukin 6 Mus musculus 95-99 30381123-8 2018 Results beta-aescin can significantly reduce the pathological changes of lung tissue, lower PaCO2 while increase PaO2 and D/W ratio, down-regulate the expression of TNF-alpha, IL-1beta and IL-6 in LPS-ALI mice. Escin 8-19 interleukin 6 Mus musculus 189-193 26159678-9 2015 In addition, Escin decreased the level of the pro-inflammatory cytokinesTNF-alpha,IL-1beta, IL-6 and HMGB1 in endotoxemic mice and in LPS-induced macrophages. Escin 13-18 interleukin 6 Mus musculus 92-96 26159678-11 2015 The release of the pro-inflammatory cytokinesTNF-alpha,IL-1beta, IL-6 could be suppressed in rHMGB1-induced macrophages by Escin. Escin 123-128 interleukin 6 Mus musculus 65-69