PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21276435-0	2011	The role of aldehyde reductase AKR1A1 in the metabolism of gamma-hydroxybutyrate in 1321N1 human astrocytoma cells.	Sodium Oxybate	59-80	aldo-keto reductase family 1 member A1	Homo sapiens	12-30	
25256836-0	2014	Metabolism of gamma hydroxybutyrate in human hepatoma HepG2 cells by the aldo-keto reductase AKR1A1.	Sodium Oxybate	14-35	aldo-keto reductase family 1 member A1	Homo sapiens	93-99	
25256836-3	2014	A high Km aldehyde reductase has previously been reported to catalyse the NADP-dependent oxidation of GHB at high concentrations.	Sodium Oxybate	102-105	aldo-keto reductase family 1 member A1	Homo sapiens	10-28	
25256836-4	2014	It is assumed that this enzyme is identical to the aldo-keto reductase AKR1A1, but its role in GHB oxidation has not been fully evaluated.	Sodium Oxybate	95-98	aldo-keto reductase family 1 member A1	Homo sapiens	71-77	
25256836-5	2014	In this study, the extent of AKR1A1 in GHB metabolism has been determined in HepG2 cells using RNA-interference technology.	Sodium Oxybate	39-42	aldo-keto reductase family 1 member A1	Homo sapiens	29-35	
25256836-8	2014	Demolishing AKR1A1 expression in HepG2 cells leads to significant 82% decrease in NADP-dependent GHB-dehydrogenase activity at high concentration (10mM) of GHB.	Sodium Oxybate	97-100	aldo-keto reductase family 1 member A1	Homo sapiens	12-18	
21276435-0	2011	The role of aldehyde reductase AKR1A1 in the metabolism of gamma-hydroxybutyrate in 1321N1 human astrocytoma cells.	Sodium Oxybate	59-80	aldo-keto reductase family 1 member A1	Homo sapiens	31-37	
21276435-1	2011	The role of the aldehyde reductase AKR1A1 in the biosynthesis of gamma-hydroxybutyrate (GHB) has been investigated in cell lines using a specific double stranded siRNA designed to knock down expression of the enzyme.	Sodium Oxybate	65-86	aldo-keto reductase family 1 member A1	Homo sapiens	16-34	
21276435-1	2011	The role of the aldehyde reductase AKR1A1 in the biosynthesis of gamma-hydroxybutyrate (GHB) has been investigated in cell lines using a specific double stranded siRNA designed to knock down expression of the enzyme.	Sodium Oxybate	65-86	aldo-keto reductase family 1 member A1	Homo sapiens	35-41	
21276435-1	2011	The role of the aldehyde reductase AKR1A1 in the biosynthesis of gamma-hydroxybutyrate (GHB) has been investigated in cell lines using a specific double stranded siRNA designed to knock down expression of the enzyme.	Sodium Oxybate	88-91	aldo-keto reductase family 1 member A1	Homo sapiens	16-34	
21276435-1	2011	The role of the aldehyde reductase AKR1A1 in the biosynthesis of gamma-hydroxybutyrate (GHB) has been investigated in cell lines using a specific double stranded siRNA designed to knock down expression of the enzyme.	Sodium Oxybate	88-91	aldo-keto reductase family 1 member A1	Homo sapiens	35-41	
6778961-3	1980	A second form of aldehyde reductase ("SSA reductase") specifically reduces succinic semialdehyde (SSA) to produce gamma-hydroxybutyrate.	Sodium Oxybate	114-135	aldo-keto reductase family 1 member A1	Homo sapiens	17-35