PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25457559-4	2015	Here, we demonstrate that brain neprilysin overexpression induced in vivo by repeated gamma-hydroxybutyrate autoadministration reduces cerebral Abeta contents and prevents cognitive deficits in APPSWE mice.	Sodium Oxybate	86-107	amyloid beta (A4) precursor protein	Mus musculus	144-149	
25457559-5	2015	Oral gamma-hydroxybutyrate also counteracted phosphoramidon-induced brain neprilysin inhibition and Abeta accumulation.	Sodium Oxybate	5-26	amyloid beta (A4) precursor protein	Mus musculus	100-105	
25457559-7	2015	Together, our results suggest that gamma-hydroxybutyrate, acting via HDAC inhibition, upregulates neprilysin to reduce Abeta level and related memory deficits.	Sodium Oxybate	35-56	amyloid beta (A4) precursor protein	Mus musculus	119-124