PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18381446-0	2008	Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.	Thioguanine	66-79	ribosomal protein S6 kinase B1	Homo sapiens	34-45	
18381446-6	2008	Consistently, short interfering RNA silencing of the 70-kDa ribosomal S6 kinase 1 (S6K1), the downstream effector of mTOR, markedly reduces 6-TG-induced autophagy.	Thioguanine	140-144	ribosomal protein S6 kinase B1	Homo sapiens	83-87	
18381446-9	2008	In conclusion, our data indicate that mTOR-S6K1 positively regulates autophagy after MMR processing of 6-TG probably through its negative feedback inhibition of Akt.	Thioguanine	103-107	ribosomal protein S6 kinase B1	Homo sapiens	43-47