PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20212268-1 2010 Estradiol-17beta (E(2)beta) and its metabolites, which are sequentially synthesized by cytochrome P450s and catechol-O-methyltransferase to form 2 and 4-hydroxyestradiol (OHE(2)) and 2- and 4-methoxestradiol (ME(2)), are elevated during pregnancy. 2 and 4-hydroxyestradiol 145-169 dihydrolipoamide branched chain transacylase E2 Homo sapiens 18-26