PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2434503-0 1987 alpha-Fetoprotein-mediated transfer of arachidonic acid into cultured cloned cells derived from a rat rhabdomyosarcoma. Arachidonic Acid 39-55 alpha-fetoprotein Rattus norvegicus 0-17 10471121-4 1999 Treatment with 5-8-11-14 eicosatetraynoic acid (ETYA), an analogue of arachidonic acid, specifically led to lower AFP mRNA levels in cultured rat yolk sac explants whereas treatment with palmitic or oleic acid did not. Arachidonic Acid 70-86 alpha-fetoprotein Rattus norvegicus 114-117 2434503-4 1987 Time course uptake of AFP and arachidonic acid by these cells exhibited a saturable profile at both 4 and 37 degrees C. A diffusible nonsaturable uptake of arachidonic acid was observed in experiments at both 4 and 37 degrees C with preparations of fixed AFP content and increased molar amounts of arachidonic acid (up to 8-fold molar excess). Arachidonic Acid 156-172 alpha-fetoprotein Rattus norvegicus 22-25 2434503-4 1987 Time course uptake of AFP and arachidonic acid by these cells exhibited a saturable profile at both 4 and 37 degrees C. A diffusible nonsaturable uptake of arachidonic acid was observed in experiments at both 4 and 37 degrees C with preparations of fixed AFP content and increased molar amounts of arachidonic acid (up to 8-fold molar excess). Arachidonic Acid 156-172 alpha-fetoprotein Rattus norvegicus 255-258 2434503-4 1987 Time course uptake of AFP and arachidonic acid by these cells exhibited a saturable profile at both 4 and 37 degrees C. A diffusible nonsaturable uptake of arachidonic acid was observed in experiments at both 4 and 37 degrees C with preparations of fixed AFP content and increased molar amounts of arachidonic acid (up to 8-fold molar excess). Arachidonic Acid 156-172 alpha-fetoprotein Rattus norvegicus 22-25 2434503-4 1987 Time course uptake of AFP and arachidonic acid by these cells exhibited a saturable profile at both 4 and 37 degrees C. A diffusible nonsaturable uptake of arachidonic acid was observed in experiments at both 4 and 37 degrees C with preparations of fixed AFP content and increased molar amounts of arachidonic acid (up to 8-fold molar excess). Arachidonic Acid 156-172 alpha-fetoprotein Rattus norvegicus 255-258 2434503-6 1987 This suggests that, under physiological conditions (low fatty acid to AFP ratio), the uptake of arachidonic acid by the tumor cells is regulated by the protein. Arachidonic Acid 96-112 alpha-fetoprotein Rattus norvegicus 70-73 2419923-0 1986 Effect of alpha-fetoprotein on arachidonic acid metabolism in the preadipocyte cell line OB 17. Arachidonic Acid 31-47 alpha-fetoprotein Rattus norvegicus 10-27 2419923-1 1986 Previous work has shown that alpha-fetoprotein (AFP) is able to bind specifically polyunsaturated fatty acids, one of the major ligands being arachidonic acid (C20:4). Arachidonic Acid 142-158 alpha-fetoprotein Rattus norvegicus 29-46 2419923-1 1986 Previous work has shown that alpha-fetoprotein (AFP) is able to bind specifically polyunsaturated fatty acids, one of the major ligands being arachidonic acid (C20:4). Arachidonic Acid 142-158 alpha-fetoprotein Rattus norvegicus 48-51 2580485-5 1985 AFP has high affinity to unsaturated fatty acids (UFA) such as arachidonic acid (C20:4) and so on. Arachidonic Acid 63-79 alpha-fetoprotein Rattus norvegicus 0-3 2413517-0 1985 Presence of three different binding sites for retinoids, bilirubin and estrogen or arachidonic acid on rat alpha-fetoprotein. Arachidonic Acid 83-99 alpha-fetoprotein Rattus norvegicus 107-124 2413517-2 1985 This site overlaps with a high affinity arachidonic acid binding site (Ka = 1 X 10(7) M-1) and with a tryptophan methyl ester binding site, AFP also possesses a second site able to bind retinoids with a Ka = 1 X 10(6) M-1, and a third site for the binding of bilirubin (Ka = 1 X 10(6) M-1). Arachidonic Acid 40-56 alpha-fetoprotein Rattus norvegicus 140-143 6193343-2 1983 Gas chromatography demonstrated a high level of oleic and linoleic acids and the presence of arachidonic acid, a strong competitor of the rat alpha-fetoprotein-estrogen interaction. Arachidonic Acid 93-109 alpha-fetoprotein Rattus norvegicus 142-159 6193343-3 1983 Arachidonic acid is a precursor of prostaglandins thus we suggest that its binding to AFP might play a role in the AFP-mediated ovarian regulation previously demonstrated. Arachidonic Acid 0-16 alpha-fetoprotein Rattus norvegicus 86-89 6193343-3 1983 Arachidonic acid is a precursor of prostaglandins thus we suggest that its binding to AFP might play a role in the AFP-mediated ovarian regulation previously demonstrated. Arachidonic Acid 0-16 alpha-fetoprotein Rattus norvegicus 115-118