PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11004609-0 2000 Arachidonic acid-containing phosphatidylcholine inhibits lymphocyte proliferation and decreases interleukin-2 and interferon-gamma production from concanavalin A-stimulated rat lymphocytes. Arachidonic Acid 0-16 interleukin 2 Rattus norvegicus 96-109 8478037-0 1993 Interleukin-2 causes endothelium-dependent contractions to arachidonic acid. Arachidonic Acid 59-75 interleukin 2 Rattus norvegicus 0-13 8478037-1 1993 The present experiments were designed to investigate the effect of interleukin-2 on the response to arachidonic acid in rings with and without endothelium from Wistar-Kyoto (WKY) and spontaneously hypertensive rat (SHR) aortas. Arachidonic Acid 100-116 interleukin 2 Rattus norvegicus 67-80 8478037-3 1993 Incubation with interleukin-2 (10 units/mL) for 6 or 18 hours augmented the response to arachidonic acid in rings with, but not in those without, endothelium from WKY rat aortas. Arachidonic Acid 88-104 interleukin 2 Rattus norvegicus 16-29 8478037-4 1993 In the WKY aorta, both the endothelium-dependent and endothelium-independent contractions to arachidonic acid observed after incubation with interleukin-2 were abolished by indomethacin and ridogrel (a thromboxane-endoperoxide receptor antagonist and a thromboxane synthase inhibitor) but were not affected by dazoxiben (a thromboxane synthase inhibitor). Arachidonic Acid 93-109 interleukin 2 Rattus norvegicus 141-154 2353306-12 1990 We believe that rIL-2 induces activation of arachidonic acid metabolism, which leads to the production of multiple inflammatory mediators that cause increased microvascular permeability and the adverse cardiopulmonary effects of rIL-2. Arachidonic Acid 44-60 interleukin 2 Rattus norvegicus 16-21 2353306-12 1990 We believe that rIL-2 induces activation of arachidonic acid metabolism, which leads to the production of multiple inflammatory mediators that cause increased microvascular permeability and the adverse cardiopulmonary effects of rIL-2. Arachidonic Acid 44-60 interleukin 2 Rattus norvegicus 229-234