PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17710403-6 2007 In addition, CPZ-treatment induces phosphorylation of the translation initiation factor (eIF2alpha), which reduces the general rate of protein synthesis and stimulates the production of Gcn4p, a major transcription factor that is activated in response to environmental stresses. Chlorpromazine 13-16 amino acid starvation-responsive transcription factor GCN4 Saccharomyces cerevisiae S288C 186-191