PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28283434-7	2017	Tertiary conformational changes probed by acrylamide quenching of Pgp tryptophan fluorescence with the drugs and a nonhydrolyzable ATP analog implied that the STT-bound Pgp must undergo larger conformational changes to hydrolyze ATP than ETT-bound Pgp.	Acrylamide	42-52	ATP binding cassette subfamily B member 1	Homo sapiens	66-69	
29499278-6	2018	Acrylamide quenching of tryptophan fluorescence to probe Pgp conformational changes revealed that methadone- and loperamide-induced conformational changes were distinct.	Acrylamide	0-10	ATP binding cassette subfamily B member 1	Homo sapiens	57-60	
28283434-7	2017	Tertiary conformational changes probed by acrylamide quenching of Pgp tryptophan fluorescence with the drugs and a nonhydrolyzable ATP analog implied that the STT-bound Pgp must undergo larger conformational changes to hydrolyze ATP than ETT-bound Pgp.	Acrylamide	42-52	ATP binding cassette subfamily B member 1	Homo sapiens	169-172	
28283434-7	2017	Tertiary conformational changes probed by acrylamide quenching of Pgp tryptophan fluorescence with the drugs and a nonhydrolyzable ATP analog implied that the STT-bound Pgp must undergo larger conformational changes to hydrolyze ATP than ETT-bound Pgp.	Acrylamide	42-52	ATP binding cassette subfamily B member 1	Homo sapiens	169-172	
26823559-7	2016	These interactions correlated to drug-induced conformational changes deduced from acrylamide quenching of Pgp tryptophan fluorescence.	Acrylamide	82-92	ATP binding cassette subfamily B member 1	Homo sapiens	106-109	
16803457-4	2006	Quenching of intrinsic Pgp tryptophan fluorescence by acrylamide, iodide and caesium indicated that conformational changes took place upon formation of the trapped complexes.	Acrylamide	54-64	ATP binding cassette subfamily B member 1	Homo sapiens	23-26	
16803457-5	2006	Trapping with V(i) and ATP led to a 6-fold increase in the acrylamide quenching constant, K(SV), suggesting that large conformational changes take place in the Pgp transmembrane regions on trapping in the forward direction.	Acrylamide	59-69	ATP binding cassette subfamily B member 1	Homo sapiens	160-163