PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1706224-1 1990 Treatment of PtK1 cells with 5 mM acrylamide for 4 hr induces reversible dephosphorylation of keratin in concert with reversible aggregation of intermediate filaments (Eckert and Yeagle, Cell Motil. Acrylamide 34-44 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 13-17 1706224-3 1990 We have examined this phenomenon by 1) in vitro phosphorylation of isolated PtK1 keratin filaments and 2) combined treatments of PtK1 cells with both acrylamide and agents which elevate intracellular cAMP levels. Acrylamide 150-160 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 76-80 1706224-3 1990 We have examined this phenomenon by 1) in vitro phosphorylation of isolated PtK1 keratin filaments and 2) combined treatments of PtK1 cells with both acrylamide and agents which elevate intracellular cAMP levels. Acrylamide 150-160 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 129-133 1706224-13 1990 These observations suggest that 1) PtK1 keratins are phosphorylated by cAMP-dependent kinase and an endogenous, cAMP-independent kinase and 2) alteration of levels of cAMP-dependent phosphorylation may be involved in aggregation of keratin filaments in response to acrylamide. Acrylamide 265-275 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 35-39 2463103-0 1988 Acrylamide treatment of PtK1 cells causes dephosphorylation of keratin polypeptides. Acrylamide 0-10 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 24-28 3698106-0 1986 Alteration of the distribution of intermediate filaments in PtK1 cells by acrylamide. Acrylamide 74-84 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 60-64 2411559-0 1985 Alteration of intermediate filament distribution in PtK1 cells by acrylamide. Acrylamide 66-76 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 52-56 2411559-1 1985 PtK1 cells were treated with low concentrations of acrylamide resulting in disruption of intermediate filament networks. Acrylamide 51-61 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 0-4