PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33128149-0	2021	Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-kappaB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways.	7-hydroxycoumarin	0-13	toll-like receptor 4	Rattus norvegicus	77-82	
34268687-0	2021	Umbelliferone alleviates hepatic ischemia/reperfusion-induced oxidative stress injury via targeting Keap-1/Nrf-2/ARE and TLR4/NF-kappaB-p65 signaling pathway.	7-hydroxycoumarin	0-13	toll-like receptor 4	Rattus norvegicus	121-125	
34268687-4	2021	Here, this study was conducted to examine the potential protective role of UMB during the early phase of hepatic IR injury via targeting Keap-1/Nrf-2/ARE and its closely related signaling pathway, TLR4/NF-kappaB-p65.	7-hydroxycoumarin	75-78	toll-like receptor 4	Rattus norvegicus	197-201	
34268687-9	2021	Besides, UMB significantly down-regulated NF-kappaB-p65 and TLR4 expressions with subsequent decreased TNF-alpha and IL-1beta levels coupled with the up-regulation of the IL-10 level.	7-hydroxycoumarin	9-12	toll-like receptor 4	Rattus norvegicus	60-64	
34268687-11	2021	Together, UMB is a promising agent for the amelioration of liver tissues against IR-induced oxidative injury through activation of the Keap-1/Nrf-2/ARE signaling pathway along with suppression of its closely related signaling pathways: TLR4/NF-kappaB-p65.	7-hydroxycoumarin	10-13	toll-like receptor 4	Rattus norvegicus	236-240