PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34583226-5	2021	We found that the phytochemical compounds, such as curcumin, naringenin, sulforaphane, diallyl disulfide, mangiferin, oleanolic acid, umbelliferone, daphnetin, quercetin, isorhamnetin-3-O-galactoside, hesperidin, diammonium glycyrrhizinate, corilagin, shikonin, farrerol, and chenpi, had the potential to improve the Nrf2-ARE signaling thereby combat hepatotoxicity.	7-hydroxycoumarin	134-147	NFE2 like bZIP transcription factor 2	Homo sapiens	317-321	
29608980-0	2018	Renoprotective effects of umbelliferone on methotrexate-induced renal injury through regulation of Nrf-2/Keap-1, P38MAPK/NF-kappaB, and apoptosis signaling pathways.	7-hydroxycoumarin	26-39	NFE2 like bZIP transcription factor 2	Homo sapiens	99-104	
28263721-0	2017	Hepatoprotective effect of 7-Hydroxycoumarin against Methyl glyoxal toxicity via activation of Nrf2.	7-hydroxycoumarin	27-44	NFE2 like bZIP transcription factor 2	Homo sapiens	95-99	
28263721-6	2017	In addition, depletion of NRF2 by siRNA significantly reduces the protective effect of 7-HC against MG, suggesting that NRF2 plays an important role in the protective function of 7-HC.	7-hydroxycoumarin	87-91	NFE2 like bZIP transcription factor 2	Homo sapiens	26-30	
28263721-6	2017	In addition, depletion of NRF2 by siRNA significantly reduces the protective effect of 7-HC against MG, suggesting that NRF2 plays an important role in the protective function of 7-HC.	7-hydroxycoumarin	87-91	NFE2 like bZIP transcription factor 2	Homo sapiens	120-124	
28263721-6	2017	In addition, depletion of NRF2 by siRNA significantly reduces the protective effect of 7-HC against MG, suggesting that NRF2 plays an important role in the protective function of 7-HC.	7-hydroxycoumarin	179-183	NFE2 like bZIP transcription factor 2	Homo sapiens	26-30	
28263721-6	2017	In addition, depletion of NRF2 by siRNA significantly reduces the protective effect of 7-HC against MG, suggesting that NRF2 plays an important role in the protective function of 7-HC.	7-hydroxycoumarin	179-183	NFE2 like bZIP transcription factor 2	Homo sapiens	120-124	
28263721-7	2017	These findings highlight the potential for the interventional activation of the NRF2 induction via the non-toxic natural phytochemical 7-HC as a novel therapeutic approach towards the detoxification of MG, with the aim of halting the progression of diseases in which MG has been implicated.	7-hydroxycoumarin	135-139	NFE2 like bZIP transcription factor 2	Homo sapiens	80-84