PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12226745-0	2002	p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol.	purvalanol B	61-71	interferon induced protein 44	Homo sapiens	4-7	
12226745-6	2002	In addition to CDK1, p42/p44 MAPK were found to be two major purvalanol-interacting proteins in five different mammalian cell lines (CCL39, PC12, HBL100, MCF-7 and Jurkat cells), suggesting the generality of the purvalanol/p42/p44 MAPK interaction.	purvalanol B	61-71	interferon induced protein 44	Homo sapiens	25-28	
12226745-12	2002	When cells were treated with purvalanol, p42/p44 MAPK and CDK1 activities were inhibited in a dose-dependent manner.	purvalanol B	29-39	interferon induced protein 44	Homo sapiens	45-48	
12226745-14	2002	We conclude that the anti-proliferative properties of purvalanol are mediated by inhibition of both p42/p44 MAPK and CDKs.	purvalanol B	54-64	interferon induced protein 44	Homo sapiens	104-107