PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30320903-8 2019 This study provides biological evidence about purvalanol and roscovitine have apoptotic and antimetastatic effects via MAPK signaling on prostate cancer cell by activation of GSK3beta signaling and inhibition of phosphoinositide-3-kinase/AKT (PI3K/AKT) pathways involved in the EMT process. purvalanol B 46-56 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 243-251