PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25901510-7 2015 HCT 116 colon cancer cells were exposed to purvalanol, which activated ER stress via upregulation of PERK, IRE1alpha gene expression, eIF-2alpha phosphorylation and ATF-6 cleavage at early time-points in the HCT 116 colon cancer cells. purvalanol B 43-53 eukaryotic translation initiation factor 2A Homo sapiens 134-144