PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30125791-7	2018	Independent of group, DEX and GTS-21 dose-dependently inhibited TNF-alpha and IL-10 production, whereas TERB inhibited TNF-alpha and upregulated IL-10 production.	Terbutaline	104-108	tumor necrosis factor	Homo sapiens	119-128	
17112600-3	2007	METHODS: We analyzed the in vitro effects of the beta-adrenergic agonist terbutaline and the glucocorticoid agonist dexamethasone on TNF-alpha and IL-10 production by LPS-stimulated monocytes in whole cell blood cultures in patients with inflammatory bowel diseases in remission (N=10), diarrhoea-predominant irritable bowel syndrome (IBS, N=12), patients with a recent gastroenteritis (post-infectious group, N=10), and healthy controls (N=15).	Terbutaline	73-84	tumor necrosis factor	Homo sapiens	133-142	
21901530-13	2011	The cells will respond to the beta-adrenergic receptor agonist terbutaline resulting in reduced TNF-alpha and increased IL-10 and IL-6 production following CEA activation.	Terbutaline	63-74	tumor necrosis factor	Homo sapiens	96-105	
17112600-5	2007	In contrast, terbutaline resulted in a concentration-dependent suppression of TNF-alpha production, which was comparable in all groups.	Terbutaline	13-24	tumor necrosis factor	Homo sapiens	78-87	
12417450-0	2002	Oral terbutaline differentially affects cytokine (IL-10, IL-12, TNF, IFNg) release in multiple sclerosis patients and controls.	Terbutaline	5-16	tumor necrosis factor	Homo sapiens	64-67	
12538816-6	2003	In the same manner, salbutanol and terbutaline as well as norepinephrine, epinephrine, and isoproterenol regulated the IL-18-induced cytokine production, including IL-12, tumor necrosis factor-alpha or interferon-gamma through the stimulation of beta 2-AR.	Terbutaline	35-46	tumor necrosis factor	Homo sapiens	171-198	
11193379-7	2000	A beta-adrenoceptor agonists (beta-agonist), procaterol, clenbuterol, fenoterol and terbutaline suppressed the production of TNF- and IL-1 beta.	Terbutaline	84-95	tumor necrosis factor	Homo sapiens	125-128	
11675405-9	2001	Terbutaline (10(-6) M to 10(-8) M) suppressed MAPK (p42/p44, p38), NF-kappa B (p50, p65), and TNF-alpha promoter activity in a dose-dependent way that was prevented by the beta(2)-adrenoceptor antagonist, ICI118,551.	Terbutaline	0-11	tumor necrosis factor	Homo sapiens	94-103	
11675405-12	2001	In summary, the downregulation of TNF-alpha transcription by terbutaline was mediated by an inhibitory effect of beta(2)-adrenoceptor activation on MAPK (p42/p44, p38) and NF-kappa B (p50/p65), which were exerted through a cAMP-PKA pathway and a cAMP-independent mechanism.	Terbutaline	61-72	tumor necrosis factor	Homo sapiens	34-43	
10469353-5	1999	Furthermore, the time course effects of terbutaline on cAMP, MAPK (p42/p44), and TNF-alpha release were evaluated in the cells.	Terbutaline	40-51	tumor necrosis factor	Homo sapiens	81-90	
10469353-10	1999	The terbutaline-induced down-regulation of IL-6 gene production was mediated by an inhibitory effect of terbutaline on TNF-alpha, which was exerted through the MAPK and cAMP pathways, whereas the up-regulation appeared to be due to a direct action of intracellular cAMP.	Terbutaline	4-15	tumor necrosis factor	Homo sapiens	119-128	
10469353-10	1999	The terbutaline-induced down-regulation of IL-6 gene production was mediated by an inhibitory effect of terbutaline on TNF-alpha, which was exerted through the MAPK and cAMP pathways, whereas the up-regulation appeared to be due to a direct action of intracellular cAMP.	Terbutaline	104-115	tumor necrosis factor	Homo sapiens	119-128	
9127437-2	1997	The beta-agonists, procaterol, clenbuterol, fenoterol and terbutaline, inhibited TNF-alpha and IL-1 beta production in a concentration-dependent manner, whereas they had no effect on IL-8 production.	Terbutaline	58-69	tumor necrosis factor	Homo sapiens	81-90