PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15449725-0 2004 Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline. Terbutaline 72-83 butyrylcholinesterase Homo sapiens 21-42 15449725-3 2004 Both bambuterol and terbutaline inhibit BChE, but their affinities differ in human serum BChE variants (U, A, F, K and S) due to their positive charge. Terbutaline 20-31 butyrylcholinesterase Homo sapiens 40-44 15449725-5 2004 Terbutaline showed competitive reversible inhibition for all BChE variants. Terbutaline 0-11 butyrylcholinesterase Homo sapiens 61-65 15449725-9 2004 The affinity of all studied BChE variants for terbutaline was low, which suggests that terbutaline originating from bambuterol hydrolysis should not affect the hydrolysis of bambuterol by BChE. Terbutaline 46-57 butyrylcholinesterase Homo sapiens 28-32 15449725-9 2004 The affinity of all studied BChE variants for terbutaline was low, which suggests that terbutaline originating from bambuterol hydrolysis should not affect the hydrolysis of bambuterol by BChE. Terbutaline 87-98 butyrylcholinesterase Homo sapiens 28-32 9643621-1 1998 AIMS: It has been assumed that both plasma cholinesterase (EC 3.1.1.8) and oxidative enzymes are needed for optimum formation of the bronchodilator terbutaline from its biscarbamate prodrug bambuterol. Terbutaline 148-159 butyrylcholinesterase Homo sapiens 43-57 9643621-11 1998 Nevertheless, the subjects with atypical cholinesterase were able to produce terbutaline as efficiently as normal subjects. Terbutaline 77-88 butyrylcholinesterase Homo sapiens 41-55 2244449-1 1990 Bambuterol (the bisdimethylcarbamate prodrug of terbutaline) is a new bronchodilator with a prolonged duration of action due to its inhibition of plasma cholinesterase during metabolism. Terbutaline 48-59 butyrylcholinesterase Homo sapiens 153-167 2239124-1 1990 Bambuterol is an inactive prodrug which is enzymatically cleaved by plasma cholinesterase to yield the active compound, terbutaline. Terbutaline 120-131 butyrylcholinesterase Homo sapiens 75-89 22817559-2 2012 One of these structurally related bronchodilators is terbutaline; it is administered as a prodrug, bambuterol, and is metabolized (bioconverted) into terbutaline by butyrylcholinesterase (BChE). Terbutaline 53-64 butyrylcholinesterase Homo sapiens 165-186 22817559-2 2012 One of these structurally related bronchodilators is terbutaline; it is administered as a prodrug, bambuterol, and is metabolized (bioconverted) into terbutaline by butyrylcholinesterase (BChE). Terbutaline 53-64 butyrylcholinesterase Homo sapiens 188-192 22817559-2 2012 One of these structurally related bronchodilators is terbutaline; it is administered as a prodrug, bambuterol, and is metabolized (bioconverted) into terbutaline by butyrylcholinesterase (BChE). Terbutaline 150-161 butyrylcholinesterase Homo sapiens 165-186 22817559-2 2012 One of these structurally related bronchodilators is terbutaline; it is administered as a prodrug, bambuterol, and is metabolized (bioconverted) into terbutaline by butyrylcholinesterase (BChE). Terbutaline 150-161 butyrylcholinesterase Homo sapiens 188-192