PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11675405-9 2001 Terbutaline (10(-6) M to 10(-8) M) suppressed MAPK (p42/p44, p38), NF-kappa B (p50, p65), and TNF-alpha promoter activity in a dose-dependent way that was prevented by the beta(2)-adrenoceptor antagonist, ICI118,551. Terbutaline 0-11 RELA proto-oncogene, NF-kB subunit Homo sapiens 84-87 11675405-12 2001 In summary, the downregulation of TNF-alpha transcription by terbutaline was mediated by an inhibitory effect of beta(2)-adrenoceptor activation on MAPK (p42/p44, p38) and NF-kappa B (p50/p65), which were exerted through a cAMP-PKA pathway and a cAMP-independent mechanism. Terbutaline 61-72 RELA proto-oncogene, NF-kB subunit Homo sapiens 188-191