PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29044437-1	2017	Coumarins are natural and synthetic active ingredients widely applied in diverse types of medicinal treatments, such as cancer, inflammation, infection, and enzyme inhibition (monoamine oxidase B).	Coumarins	0-9	monoamine oxidase B	Homo sapiens	176-195	
24393810-1	2014	A series of 6-substituted 3-(pyrrolidin-1-ylmethyl)chromen-2-ones (coumarins) have been synthesized and their inhibitory activity to human monoamine oxidase A (MAO A) and B (MAO B) determined.	Coumarins	67-76	monoamine oxidase B	Homo sapiens	174-179	
24782464-6	2014	6-Chloro-3-phenylcoumarins unsubstituted at the 4 position were found to be more active as MAO-B inhibitors than the corresponding 4-hydroxylated coumarins.	Coumarins	17-26	monoamine oxidase B	Homo sapiens	91-96	
28245770-4	2017	Chromones are structurally related to a series of coumarins and chalcones, which are well-known inhibitors of MAO-B.	Coumarins	50-59	monoamine oxidase B	Homo sapiens	110-115	
24934993-1	2014	Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the researchers to develop novel synthetic and semisynthetic coumarin based therapeutic agents.	Coumarins	20-29	monoamine oxidase B	Homo sapiens	118-123	
23231391-9	2012	Different families of nitrogen and oxygen heterocycles, such as pyrazoles, hydrazinylthiazoles, xanthones, coumarins or chromones have also been extensively used as scaffolds in medicinal chemistry programs for searching novel MAO-B inhibitors.	Coumarins	107-116	monoamine oxidase B	Homo sapiens	227-232	
23231397-4	2012	Differently substituted coumarins have been synthesized and evaluated as MAO-A and MAO-B inhibitors.	Coumarins	24-33	monoamine oxidase B	Homo sapiens	83-88	
21316817-5	2011	According to our results, docking experiments could be an interesting approach to try to predict the activity of this class of coumarins against MAO-B receptors.	Coumarins	127-136	monoamine oxidase B	Homo sapiens	145-150	
35168478-3	2022	A recent study has shown that coumarins tend to be more selective towards MAO-B than MAO-A when connected to a hex-5-ynyloxy chain at position 6 in contrast to their C7-isomers.	Coumarins	30-39	monoamine oxidase B	Homo sapiens	74-79