PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17409144-7 2007 This G2/M arrest in response to nocodazole was also abolished by caffeine, suggesting an involvement of the ATM/ATR signaling pathway in the regulation of this cell cycle checkpoint. Nocodazole 32-42 ATM serine/threonine kinase Homo sapiens 108-111 22285910-8 2012 Unlike cisplatin, which causes DNA damage in each phase of the cell cycle, VNR and nocodazole induced aberrant JNK-regulated DNA damage in prometaphase; however, inhibiting ATM (ataxia telangiectasia, mutated) and ATR (ATM and Rad3-related) did not reverse mitotic arrest or apoptosis. Nocodazole 83-93 ATM serine/threonine kinase Homo sapiens 173-176 17409144-8 2007 Importantly, we show that the direct interaction of EBNA3C with Chk2, the ATM/ATR signaling effector, is responsible for the release of this nocodazole-induced G2/M arrest and that this interaction leads to the serine 216 phosphorylation of Cdc25c, which is sequestered in the cytoplasm by 14-3-3. Nocodazole 141-151 ATM serine/threonine kinase Homo sapiens 74-77 16319535-5 2006 When mitotic spindle is disrupted by nocodazole, ATM is displaced from centrosomes and colocalizes with phospho-Ser15-p53 under the form of spots dispersed in the mitotic cytoplasm. Nocodazole 37-47 ATM serine/threonine kinase Homo sapiens 49-52 11591318-5 2001 This Pin2/TRF1 activity can be significantly potentiated by the microtubule-disrupting agent nocodazole [12] but is suppressed by phosphorylation of Pin2/TRF1 by ATM; this negative regulation is important for preventing apoptosis upon DNA damage [13]. Nocodazole 93-103 ATM serine/threonine kinase Homo sapiens 162-165