PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20098744-5 2010 Nocodazole stimulates RhoA activity, and inhibition of the RhoA target ROCK allows nocodazole-treated cells to re-establish lamellipodia and uropods and persistent migratory polarity. Nocodazole 0-10 ras homolog family member A Homo sapiens 22-26 12409284-8 2003 Disruption of the MT network by prolonged treatments with low doses of either nocodazole or paclitaxel before the application of strain abolished the redistribution of RhoA and Rac in response to the applied forces. Nocodazole 78-88 ras homolog family member A Homo sapiens 168-172 33229726-5 2021 Treatment of Schwann cells with a Ras homolog family member (Rho) GTPase inhibitor and small interfering RNA targeting Rho or cytoskeleton disrupting agents, such as nocodazole or cytochalasin D, revealed that hypotonicity-induced ATP release depended on intracellular RhoA and the cytoskeleton. Nocodazole 166-176 ras homolog family member A Homo sapiens 269-273 32789168-6 2020 Upon nocodazole-induced microtubule disassembly, the interaction between BNIP-2 and GEF-H1 increases, while knockdown of BNIP-2 reduces RhoA activation and cell rounding via uncoupling RhoA-GEF-H1 interaction. Nocodazole 5-15 ras homolog family member A Homo sapiens 185-189 20098744-5 2010 Nocodazole stimulates RhoA activity, and inhibition of the RhoA target ROCK allows nocodazole-treated cells to re-establish lamellipodia and uropods and persistent migratory polarity. Nocodazole 83-93 ras homolog family member A Homo sapiens 59-63 18287519-0 2008 GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA. Nocodazole 15-25 ras homolog family member A Homo sapiens 84-88 18287519-6 2008 Furthermore, the nocodazole-induced activation of RhoA and Rho-associated kinase (ROCK) that mediates phosphorylation of myosin regulatory light chain (MLC) is impaired in GEF-H1-depleted cells. Nocodazole 17-27 ras homolog family member A Homo sapiens 50-54 18287519-8 2008 Our studies reveal a critical role for a GEF-H1/RhoA/ROCK/MLC signaling pathway in mediating nocodazole-induced cell contractility. Nocodazole 93-103 ras homolog family member A Homo sapiens 48-52