PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18451172-4 2008 In contrast, the addition of low-dose TRAIL to nocodazole was associated with maximally increased caspase-3, caspase-8, and caspase-9 activation, which efficiently abrogated the mitotic delay and markedly increased cell death. Nocodazole 47-57 TNF superfamily member 10 Homo sapiens 38-43 18451172-6 2008 The addition of TRAIL to either nocodazole or paclitaxel (Taxol) reduced levels of the mitotic checkpoint proteins BubR1 and Bub1. Nocodazole 32-42 TNF superfamily member 10 Homo sapiens 16-21 18451172-7 2008 BubR1 mutated for the caspase cleavage sites, but not wild-type BubR1, was resistant to cleavage induced by TRAIL added to nocodazole, and partially blocked the checkpoint abrogation. Nocodazole 123-133 TNF superfamily member 10 Homo sapiens 108-113 18393775-4 2008 The microtubule inhibitors taxol, nocodazole, and colcemid, as well as an inhibitor of actin microfilaments cytochalasin D, enhance the action of TRAIL and allow it to overcome protection caused by overexpression of Bcl-2. Nocodazole 34-44 TNF superfamily member 10 Homo sapiens 146-151 16229016-8 2006 Conversely, microtubule disruption and Golgi scattering induced with Nocodazole treatment inhibited TRAIL-increased NOS activity, indicating that, on cultured HUVEC, TRAIL ability to affect NO production by regulating eNOS sub-cellular distribution is mediated by cytoskeleton and Golgi complex modifications. Nocodazole 69-79 TNF superfamily member 10 Homo sapiens 100-105 16229016-8 2006 Conversely, microtubule disruption and Golgi scattering induced with Nocodazole treatment inhibited TRAIL-increased NOS activity, indicating that, on cultured HUVEC, TRAIL ability to affect NO production by regulating eNOS sub-cellular distribution is mediated by cytoskeleton and Golgi complex modifications. Nocodazole 69-79 TNF superfamily member 10 Homo sapiens 166-171