PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18451172-4	2008	In contrast, the addition of low-dose TRAIL to nocodazole was associated with maximally increased caspase-3, caspase-8, and caspase-9 activation, which efficiently abrogated the mitotic delay and markedly increased cell death.	Nocodazole	47-57	caspase 3	Homo sapiens	98-107	
21613548-4	2011	When satisfaction of the MC was prevented with 500 nM nocodazole or 2.5 muM dimethylenastron (an Eg5 inhibitor), 92-100% of RPE-1 cells slipped from mitosis in the presence of pan-caspase inhibitors or after simultaneously depleting caspase-3 and -9, and they did so with the same kinetics (~21-22 h) as after treatment with nocodazole or Eg5 inhibitors alone.	Nocodazole	54-64	caspase 3	Homo sapiens	233-249	
16906355-4	2007	Li(+) 5 mM also decreased caspase-3 activation induced by nocodazole and S/K deprivation as measured by Ac-DEVD-p-nitroaniline and the breakdown of alpha-spectrin.	Nocodazole	58-68	caspase 3	Homo sapiens	26-35	
18242119-11	2008	In addition, nocodazole-induced apoptosis involves the apical caspase-8 and -9 and the effector caspase-3.	Nocodazole	13-23	caspase 3	Homo sapiens	96-105	
16532268-0	2006	Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint.	Nocodazole	84-94	caspase 3	Homo sapiens	0-9	
16532268-4	2006	Pretreatment of human hepatoma cells with a caspase 3 inhibitor z-DEVD-FMK, prior to the treatment with an antimicrotubule drug nocodazole, abrogates the mitotic arrest, suggesting that caspase 3 (or a caspase 3-like enzyme) might be involved in mitotic-spindle checkpoint.	Nocodazole	128-138	caspase 3	Homo sapiens	186-195	
16532268-4	2006	Pretreatment of human hepatoma cells with a caspase 3 inhibitor z-DEVD-FMK, prior to the treatment with an antimicrotubule drug nocodazole, abrogates the mitotic arrest, suggesting that caspase 3 (or a caspase 3-like enzyme) might be involved in mitotic-spindle checkpoint.	Nocodazole	128-138	caspase 3	Homo sapiens	186-195	
16532268-5	2006	The studies not only characterize caspase 3 as a cell cycle-regulated protein, but also link the protein to nocodazole-dependent mitotic checkpoint, greatly expanding the understanding of caspase 3.	Nocodazole	108-118	caspase 3	Homo sapiens	188-197	
15817572-9	2005	The results showed that when caspase-3 activity was impaired, in the parental MCF-7 cell line or in the MCF-7casp-3 cells in the presence of the caspase-3 inhibitor, the frequencies of nocodazole or MMS induced micronuclei decreased.	Nocodazole	185-195	caspase 3	Homo sapiens	29-38	
15817572-9	2005	The results showed that when caspase-3 activity was impaired, in the parental MCF-7 cell line or in the MCF-7casp-3 cells in the presence of the caspase-3 inhibitor, the frequencies of nocodazole or MMS induced micronuclei decreased.	Nocodazole	185-195	caspase 3	Homo sapiens	145-154