PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32610574-6	2020	Apigenin (100 muM) significantly inhibited nitric oxide (NO) production, cytokine expression (interleukin (IL)-1beta, IL6, cyclooxygenase (COX)-2, and inducible nitric oxide synthase [iNOS]), and phosphorylation of mitogen-activated protein kinase (MAPK) signal molecules, including extracellular signal-regulated kinase (ERK) and c-Jun N-terminal protein kinase (JNK) in RAW264.7 cells.	Apigenin	0-8	nitric oxide synthase 2, inducible	Mus musculus	151-182	
10506109-5	1999	Of those compounds tested, apigenin was the most potent inhibitor of transcriptional activation of both COX-2 and iNOS.	Apigenin	27-35	nitric oxide synthase 2, inducible	Mus musculus	114-118	
32610574-6	2020	Apigenin (100 muM) significantly inhibited nitric oxide (NO) production, cytokine expression (interleukin (IL)-1beta, IL6, cyclooxygenase (COX)-2, and inducible nitric oxide synthase [iNOS]), and phosphorylation of mitogen-activated protein kinase (MAPK) signal molecules, including extracellular signal-regulated kinase (ERK) and c-Jun N-terminal protein kinase (JNK) in RAW264.7 cells.	Apigenin	0-8	nitric oxide synthase 2, inducible	Mus musculus	184-188	
19685877-6	2009	Furthermore, EEAP, apigenin, curcumin, and pinocembrin decreased LPS-mediated induction of protein and mRNA expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in RAW 264.7 cells.	Apigenin	19-27	nitric oxide synthase 2, inducible	Mus musculus	122-153	
25800110-11	2015	Moreover, apigenin or fluoxetine significantly suppressed the inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression at both the mRNA and protein level via the modulation of nuclear factor-kappaB (NF-kappaB) activation in the prefrontal cortex.	Apigenin	10-18	nitric oxide synthase 2, inducible	Mus musculus	62-93	
25800110-11	2015	Moreover, apigenin or fluoxetine significantly suppressed the inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression at both the mRNA and protein level via the modulation of nuclear factor-kappaB (NF-kappaB) activation in the prefrontal cortex.	Apigenin	10-18	nitric oxide synthase 2, inducible	Mus musculus	95-99	
24291393-5	2014	Despite the relatively weak anti-diabetic and anti-AD potentials, apigenin showed powerful antiinflammatory activity by inhibiting NO production and iNOS and COX-2 expression while vitexin and isovitexin were inactive.	Apigenin	66-74	nitric oxide synthase 2, inducible	Mus musculus	149-153	
19685877-6	2009	Furthermore, EEAP, apigenin, curcumin, and pinocembrin decreased LPS-mediated induction of protein and mRNA expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in RAW 264.7 cells.	Apigenin	19-27	nitric oxide synthase 2, inducible	Mus musculus	155-159