PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32425778-0 2020 Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway. Apigenin 0-8 sirtuin 1 Mus musculus 71-76 32425778-10 2020 Furthermore, SIRT1 inhibitor EX-527 reduced protection by API against APAP-induced hepatotoxicity. Apigenin 58-61 sirtuin 1 Mus musculus 13-18 32425778-12 2020 API prevents APAP-induced liver injury by regulating the SIRT1-p53 axis, thereby promoting APAP-induced autophagy and ameliorating APAP-induced inflammatory responses and oxidative stress injury. Apigenin 0-3 sirtuin 1 Mus musculus 57-62 33114025-6 2020 QCT, RSV and API also prevented mitochondrial dysfunction in 7KC-treated cells by counteracting the loss of mitochondrial membrane potential (PsiDeltam) and attenuating the decreased gene expression and/or protein level of AMP-activated protein kinase alpha (AMPKalpha), sirtuin 1 (SIRT1) and peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) implicated in mitochondrial biogenesis. Apigenin 13-16 sirtuin 1 Mus musculus 271-280 33114025-6 2020 QCT, RSV and API also prevented mitochondrial dysfunction in 7KC-treated cells by counteracting the loss of mitochondrial membrane potential (PsiDeltam) and attenuating the decreased gene expression and/or protein level of AMP-activated protein kinase alpha (AMPKalpha), sirtuin 1 (SIRT1) and peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) implicated in mitochondrial biogenesis. Apigenin 13-16 sirtuin 1 Mus musculus 282-287