PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8335576-10	1993	SKF 525-A and metyrapone, inhibitors of cytochrome P-450 monooxygenases, converted the cooling-induced contractions of preparations with epithelium to relaxations and had no significant effects on the responses of preparations without epithelium.	Metyrapone	14-24	Cytochrome P450 1A1	Canis lupus familiaris	40-56	
10484447-9	1999	The ACh-induced vasodilation remaining after L-NMMA and indomethacin was completely blocked by the large-conductance potassium-channel antagonist iberiotoxin or by epicardial suffusion of miconazole or metyrapone, inhibitors of cytochrome P-450 enzymes.	Metyrapone	202-212	Cytochrome P450 1A1	Canis lupus familiaris	228-244	
10901696-6	2000	The reactions required NADPH as a cofactor and were significantly inhibited by the various inhibitors of cytochrome P450 (i.e., CO, n-octylamine, SKF 525-A, metyrapone, and alpha-naphthoflavone).	Metyrapone	157-167	Cytochrome P450 1A1	Canis lupus familiaris	105-120