PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27359351-5	2016	OCA markedly inhibits hepatic cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) partly through inducing small heterodimer partner, leading to reduced bile acid pool size and altered bile acid composition, with the alpha/beta-muricholic acid proportion in bile increased by 2.6-fold and taurocholic acid (TCA) level reduced by 71%.	Taurocholic Acid	316-332	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	30-60	
8354958-0	1993	Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice.	Taurocholic Acid	34-46	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	50-81	
27359351-5	2016	OCA markedly inhibits hepatic cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) partly through inducing small heterodimer partner, leading to reduced bile acid pool size and altered bile acid composition, with the alpha/beta-muricholic acid proportion in bile increased by 2.6-fold and taurocholic acid (TCA) level reduced by 71%.	Taurocholic Acid	316-332	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	62-68	
27359351-5	2016	OCA markedly inhibits hepatic cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) partly through inducing small heterodimer partner, leading to reduced bile acid pool size and altered bile acid composition, with the alpha/beta-muricholic acid proportion in bile increased by 2.6-fold and taurocholic acid (TCA) level reduced by 71%.	Taurocholic Acid	334-337	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	30-60	
27359351-5	2016	OCA markedly inhibits hepatic cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) partly through inducing small heterodimer partner, leading to reduced bile acid pool size and altered bile acid composition, with the alpha/beta-muricholic acid proportion in bile increased by 2.6-fold and taurocholic acid (TCA) level reduced by 71%.	Taurocholic Acid	334-337	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	62-68	
27359351-6	2016	Overexpression of Cyp8b1 or concurrent overexpression of Cyp7a1 and Cyp8b1 normalizes TCA level, bile acid composition, and intestinal cholesterol absorption.	Taurocholic Acid	86-89	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	57-63