PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32187752-7 2020 Currently, the most promising potential drug candidate to slow AAA growth is metformin, and RCTs to verify or reject this hypothesis are warranted. Metformin 77-86 AAA1 Homo sapiens 63-66 30936409-1 2019 OBJECTIVE: To assess the association of metformin prescription with the risk of aortic aneurysm, aortic aneurysm events and the enlargement of abdominal aortic aneurysm (AAA). Metformin 40-49 AAA1 Homo sapiens 170-173 30936409-9 2019 We found that metformin prescription could significantly limit the enlargement of aortic aneurysm (weighted mean difference: -0.83 mm/year, 95% CI -1.38 to -0.28, I2=89.6%) among patients with AAA. Metformin 14-23 AAA1 Homo sapiens 193-196 30936409-11 2019 CONCLUSIONS: According to the available epidemiological evidence, metformin prescription could limit the expansion of AAA among patients with this disease, and may be involved with a lower incidence of aortic aneurysm and aortic aneurysm events. Metformin 66-75 AAA1 Homo sapiens 118-121 30936409-12 2019 Randomised controlled trials are needed to confirm whether metformin could reduce the enlargement of AAA in patients with or without diabetes. Metformin 59-68 AAA1 Homo sapiens 101-104