PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35222699-11 2022 Regarding the mechanism, in cartilage, metformin increased the expression of Col II and decreased the expression of MMP-13, NLRP3, caspase-1, GSDMD and IL-1beta. Metformin 39-48 gasdermin D Mus musculus 142-147 32480011-6 2020 GSDMD positive cells and NLRP3 inflammasome expression were augmented in gingival tissue, which were partly reversed by metformin. Metformin 120-129 gasdermin D Mus musculus 0-5