PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27775072-4	2017	Metformin acts by upregulating microRNA let-7 through AMPK activation, leading to degradation of H19 long noncoding RNA, which normally binds to and inactivates SAHH.	Metformin	0-9	H19 imprinted maternally expressed transcript	Homo sapiens	97-100	
31391459-0	2019	Correction: H19 lncRNA alters methylation and expression of Hnf4alpha in the liver of metformin-exposed fetuses.	Metformin	86-95	H19 imprinted maternally expressed transcript	Homo sapiens	12-15	
30192003-0	2019	Long noncoding RNA H19 participates in metformin-mediated inhibition of gastric cancer cell invasion.	Metformin	39-48	H19 imprinted maternally expressed transcript	Homo sapiens	19-22	
30192003-5	2019	We found that lncRNA H19 was greatly downregulated in gastric cancer cells treated with metformin using lncRNA microassays.	Metformin	88-97	H19 imprinted maternally expressed transcript	Homo sapiens	21-24	
30192003-9	2019	In summary, metformin has a profound antitumor effect on gastric cancer cells, and H19 is a key component in the process of metformin suppressing gastric cancer cell invasion.	Metformin	124-133	H19 imprinted maternally expressed transcript	Homo sapiens	83-86	
29215608-0	2017	H19 lncRNA alters methylation and expression of Hnf4alpha in the liver of metformin-exposed fetuses.	Metformin	74-83	H19 imprinted maternally expressed transcript	Homo sapiens	0-3	
29215608-7	2017	We also provide evidence that altered H19 expression is a direct effect of metformin in the fetal liver.	Metformin	75-84	H19 imprinted maternally expressed transcript	Homo sapiens	38-41	
29215608-8	2017	Our results suggest that metformin from the mother can directly act upon the fetal liver to modify Hnf4alpha expression, a key factor for both liver development and function, and that perturbation of this H19/Hnf4alpha-mediated pathway may contribute to the fetal origin of adult metabolic abnormalities.	Metformin	25-34	H19 imprinted maternally expressed transcript	Homo sapiens	205-208	
27775072-6	2017	This metformin-induced H19 repression and alteration of gene methylation are recapitulated in endometrial cancer tissue samples obtained from patients treated with antidiabetic doses of metformin.	Metformin	5-14	H19 imprinted maternally expressed transcript	Homo sapiens	23-26	
27775072-6	2017	This metformin-induced H19 repression and alteration of gene methylation are recapitulated in endometrial cancer tissue samples obtained from patients treated with antidiabetic doses of metformin.	Metformin	186-195	H19 imprinted maternally expressed transcript	Homo sapiens	23-26