PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30607342-16 2018 Treatment with metformin showed ability to attenuate upregulation of IL-4-DUOX2 pathway and other pathological damages to the lung after exposure to a high dose of IR. Metformin 15-24 dual oxidase 2 Rattus norvegicus 74-79 31565651-11 2018 Results showed an upregulation of both DUOX1 and DUOX2 pathways in the presence of metformin, while the level of IL-13 did not show any significant change. Metformin 83-92 dual oxidase 2 Rattus norvegicus 49-54